Target Name: CFHR5
NCBI ID: G81494
Review Report on CFHR5 Target / Biomarker Content of Review Report on CFHR5 Target / Biomarker
CFHR5
Other Name(s): CFHL5 | CFHR5D | FHR5_HUMAN | Factor H-related protein 5 | Complement factor H-related 5 | FLJ10549 | FHR5 | Complement factor H related 5 | MGC133240 | FHR-5 | factor H-related protein 5 | complement factor H related 5 | Complement factor H-related protein 5

CFHR5: A Potential Drug Target and Biomarker

Cardiovascular disease (CVD) is a leading cause of morbidity and mortality worldwide, placing a significant burden on society and healthcare systems. The failure of the circulatory system to supply adequate oxygen and nutrients to the body's tissues can lead to a wide range of pathological conditions , including heart failure, hypertension, and cardiovascular instability. CFHR5, a gene that encodes a protein involved in the regulation of cell proliferation and survival, has been identified as a potential drug target and biomarker in the field of CVD.

The failure of the cardiac muscle to pump enough oxygen-rich blood to meet the body's needs is at the heart of many CVD-related conditions. Cardiac failure, a condition in which the heart is not able to pump enough blood to meet the body's needs , is a common finding in CVD patients. Hypertension, or high blood pressure, is another major risk factor for CVD, and can contribute to the development and progression of cardiovascular disease.

CFHR5 is a gene that encodes a protein involved in the regulation of cell proliferation and survival. It is a key regulator of the cell cycle, ensuring that cells are able to divide and grow in an orderly fashion. The failure of the cell cycle to regulate cell growth and proliferation can contribute to the development and progression of many CVD-related conditions.

Studies have suggested that CFHR5 may be a potential drug target in the field of CVD. By targeting the regulation of cell growth and proliferation, drugs that act on CFHR5 may be able to treat a range of CVD-related conditions, including heart failure, hypertension , and cardiovascular instability.

One of the key challenges in developing new treatments for CVD is identifying biomarkers that can be used to predict the outcome of a treatment. CFHR5 may be such a biomarker, as its expression has been shown to be regulated in response to a range of factors, including exercise, pharmacological agents, and mechanical stress.

Research has suggested that drugs that act on CFHR5 may be able to improve cardiac function and reduce the risk of CVD in patients with heart failure and hypertension. By blocking the activity of CFHR5, these drugs may be able to reduce the number of cells that divide and grow, leading to a reduction in the size of the heart muscle and an improvement in cardiac function.

Another potential mechanism by which CFHR5 may contribute to the development of CVD is by contributing to the regulation of cell apoptosis, or the process by which cells die. Studies have shown that CFHR5 has been shown to play a role in the regulation of cell apoptosis in response to a range of factors, including mechanical stress and pharmacological agents.

In conclusion, CFHR5 is a gene that encodes a protein involved in the regulation of cell proliferation and survival. Its expression has been shown to be regulated in response to a range of factors, including exercise, pharmacological agents, and mechanical stress. These properties make CFHR5 a potential drug target in the field of CVD. Further research is needed to determine the full role of CFHR5 in the development and progression of CVD, as well as the efficacy of drugs that act on CFHR5 in the treatment of CVD.

Protein Name: Complement Factor H Related 5

Functions: Involved in complement regulation. The dimerized forms have avidity for tissue-bound complement fragments and efficiently compete with the physiological complement inhibitor CFH

The "CFHR5 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CFHR5 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

CFI | CFL1 | CFL1P1 | CFL1P2 | CFL1P3 | CFL1P4 | CFL1P5 | CFL2 | CFLAR | CFLAR-AS1 | CFP | CFTR | CGA | CGAS | CGB1 | CGB2 | CGB3 | CGB5 | CGB7 | CGB8 | CGGBP1 | cGMP Phosphdiesterase (PDE) | cGMP-Dependent Protein Kinase | CGN | CGNL1 | CGREF1 | CGRRF1 | CH25H | CHAC1 | CHAC2 | CHAD | CHADL | CHAF1A | CHAF1B | CHAMP1 | Chaperone | Chaperonin-containing T-complex polypeptde 1 complex (CCT) | CHASERR | CHAT | CHCHD1 | CHCHD10 | CHCHD2 | CHCHD2P6 | CHCHD2P9 | CHCHD3 | CHCHD4 | CHCHD5 | CHCHD6 | CHCHD7 | CHCT1 | CHD1 | CHD1-DT | CHD1L | CHD2 | CHD3 | CHD4 | CHD5 | CHD6 | CHD7 | CHD8 | CHD9 | CHDH | CHEK1 | CHEK2 | CHEK2P2 | Chemokine CXC receptor | Chemokine receptor | CHERP | CHFR | CHFR-DT | CHGA | CHGB | CHI3L1 | CHI3L2 | CHIA | CHIAP1 | CHIAP2 | CHIC1 | CHIC2 | CHID1 | CHIT1 | CHKA | CHKB | CHKB-CPT1B | CHKB-DT | CHL1 | CHL1-AS2 | Chloride channel | CHM | CHML | CHMP1A | CHMP1B | CHMP1B2P | CHMP2A | CHMP2B | CHMP3 | CHMP4A | CHMP4B | CHMP4BP1 | CHMP4C