Target Name: CGA
NCBI ID: G1081
Review Report on CGA Target / Biomarker Content of Review Report on CGA Target / Biomarker
CGA
Other Name(s): Chorionic gonadotrophin subunit alpha | Luteinizing hormone alpha chain | Thyrotropin alpha chain | follitropin alpha chain | FSHA | CGA variant 2 | Follitropin alpha chain | chorionic gonadotropin, alpha polypeptide | Glycoprotein hormones, alpha polypeptide | Choriogonadotropin alpha chain | Anterior pituitary glycoprotein hormones common subunit alpha | GPHa | lutropin alpha chain | GLHA_HUMAN | CG-ALPHA | follicle-stimulating hormone alpha subunit | Lutropin alpha chain | anterior pituitary glycoprotein hormones common subunit alpha | follicle-stimulating hormone alpha chain | thyrotropin alpha chain | Chorionic gonadotropin, alpha polypeptide | GPA1 | TSH-alpha | glycoprotein hormones, alpha polypeptide | choriogonadotropin alpha chain | luteinizing hormone alpha chain | thyroid-stimulating hormone alpha chain | Glycoprotein hormones, alpha polypeptide, transcript variant 2 | Follicle-stimulating hormone alpha chain | HCG | FSH-alpha | chorionic gonadotrophin subunit alpha | Thyroid-stimulating hormone alpha chain | Glycoprotein hormones alpha chain (isoform 2) | LHA | CG-alpha | TSHA | Glycoprotein hormones alpha chain | GPHA1 | LSH-alpha

CGA: Key Regulator of GNT Signaling in Reproductive Cells

CGA (Chorionic gonadotrophin subunit alpha) is a protein that is expressed in the testes and placenta, and it is a key regulator of gonadotropin (GNT) signaling in reproductive cells. GNT is a hormone that plays a crucial role in the development and maintenance of male reproductive organs, including testes, vas deferens, and epididymis. In addition to its role in reproductive function, CGA is also involved in a variety of physiological processes in the body, including fetal development and tissue repair.

CGA is a member of the GNT signaling pathway, which is a complex intracellular signaling pathway that is involved in the regulation of a wide range of physiological processes in the body. GNT signaling is a highly conserved pathway that is involved in the development and maintenance of tissues and organs, including reproductive organs.

CGA is expressed in the testes and placenta and plays a critical role in the regulation of GNT signaling in these tissues. It is a key regulator of the negative feedback loop that regulates the activity of the GNT receptor, which is a protein that is expressed in the testes and placenta and plays a crucial role in the regulation of male reproductive function.

In addition to its role in GNT signaling, CGA is also involved in a variety of other physiological processes in the body. For example, it is involved in the regulation of fetal development and has been shown to play a critical role in the development and maintenance of the brain and nervous system. CGA is also involved in the regulation of tissue repair and has been shown to play a critical role in the regulation of wound healing and tissue regeneration.

CGA is a potential drug target and has been shown to be involved in a variety of therapeutic processes in the body. For example, studies have shown that inhibition of CGA can lead to increased levels of GNT in the testes and placenta, which can result in improved fertility and fetal development. In addition, CGA has also been shown to play a critical role in the regulation of fetal brain development and has been shown to be involved in the development and maintenance of the nervous system.

CGA is also a potential biomarker for a variety of reproductive and neurological disorders. For example, studies have shown that levels of CGA are often decreased in men with infertility, and decreased levels of CGA have been associated with a variety of neurological disorders, including Alzheimer's disease and Parkinson's disease.

In conclusion, CGA is a protein that is expressed in the testes and placenta and plays a critical role in the regulation of GNT signaling in reproductive cells. It is involved in a variety of physiological processes in the body, including fetal development and tissue repair, and has been shown to play a critical role in the development and maintenance of the brain and nervous system. CGA is a potential drug target and biomarker for a variety of reproductive and neurological disorders, and its research may have important implications for the treatment of these disorders.

Protein Name: Glycoprotein Hormones, Alpha Polypeptide

Functions: Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH, follitropin/follicle stimulating hormone/FSH and choriogonadotropin/CG. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways

The "CGA Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CGA comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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