KRTAP1-1: A Potential Drug Target Or Biomarker for Skin Diseases

Target Name: KRTAP1-1

NCBI ID: G81851

KRTAP1-1

KRTAP1-1: A Potential Drug Target Or Biomarker for Skin Diseases

KRTAP1-1 (High sulfur keratin-associated protein 1.1) is a protein that has been identified as a potential drug target or biomarker in the field of skin diseases. The protein is expressed in high levels in the skin and is associated with various skin conditions , including dry skin, eczema, and psoriasis.

KRTAP1-1 has been shown to play a role in the regulation of cell growth, differentiation, and death, as well as in the development and maintenance of the skin barrier. It is a member of the keratin family, which is known for its role in the development and maintenance of hair and nails.

Recent studies have shown that KRTAP1-1 is involved in a number of important processes in the skin, including the regulation of cell death and the maintenance of tissue homeostasis. It has been shown to play a role in the development of skin aging, as well as in the regulation of skin response to various stimuli, such as inflammation and irritation.

As a potential drug target, KRTAP1-1 has the potential to be used to treat a variety of skin diseases, including dry skin, eczema, and psoriasis. These conditions are characterized by inflammation and/or tissue damage in the skin, and can be treated with a variety of medications, including topical creams, ointments, and systemic medications. However, there is a need for new and effective treatments for these conditions, and KRTAP1-1 may provide a promising new target for drug development.

In addition to its potential as a drug target, KRTAP1-1 has also been shown to be a potential biomarker for the diagnosis and monitoring of skin diseases. The protein is often expressed at high levels in the skin, and can be used as a diagnostic marker for conditions such as dry skin, eczema, and psoriasis. It may also be used as a marker for the assessment of the effectiveness of treatments for these conditions.

Overall, KRTAP1-1 is a protein that has the potential to be a valuable drug target or biomarker in the field of skin diseases. Further research is needed to fully understand its role in these conditions and to develop effective treatments.

Protein Name: Keratin Associated Protein 1-1

Functions: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins

The "KRTAP1-1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about KRTAP1-1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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