ZNF416: A Potential Drug Target and Biomarker (G55659)
ZNF416: A Potential Drug Target and Biomarker
ZNF416 (ZN416_HUMAN), a protein encoded by the ZNF4 gene, is a crucial regulator of cellular processes that are essential for various physiological functions. The ZNF4 gene is a member of the Zinc Finger Nucleotide (ZFN) gene family, which is known for their ability to regulate gene expression and play a role in the development and progression of various diseases, including cancer. ZNF416 has been identified as a potential drug target and biomarker for various diseases, including cancer.
The ZNF4 gene is located on chromosome 16p36 and encodes a protein that consists of 215 amino acid residues. The protein has several unique features that make it an attractive candidate for drug targeting. First, it has a Zinc Finger Nucleotide (ZFN) domain, which is known for its ability to bind to small molecules with high affinity. ZFNs have been shown to be involved in various cellular processes, including DNA replication, transcription, and RNA processing. Second, the ZNF4 protein has a nuclear localization signal (NLS), which is a unique feature that is present in a subset of ZFN proteins. NLS is known to play a role in the stability and localization of ZFN proteins, and it is possible that ZNF416 may use NLS to ensure that it is properly targeted to specific cellular locations.
The ZNF4 gene is expressed in various tissues and organs, including liver, lung, and brain, and it has been shown to play a role in various cellular processes, including cell growth, differentiation, and survival. ZNF416 has been shown to regulate the expression of other genes, including PAXL1, TCF7L1, and NF17, which are involved in cell adhesion, migration, and survival.
In addition to its role in cellular processes, ZNF416 has also been shown to be involved in the development and progression of various diseases, including cancer. For example, ZNF416 has been shown to be involved in the development and progression of colon cancer, by regulating the expression of genes involved in cell adhesion, migration, and survival.
Given its unique features and its involvement in various cellular processes, ZNF416 has potential as a drug target and biomarker. Researchers have been interested in developing compounds that can specifically target ZNF416 and modulate its activity. One approach that has been explored is the use of small molecules, such as inhibitors or modulators of ZNF416, to treat various diseases, including cancer.
In conclusion, ZNF416 is a unique and highly conserved protein that has the potential to be a drug target and biomarker for various diseases. Its unique features, including the ZFN domain and NLS, make it an attractive candidate for drug targeting, and its involvement in various cellular processes and its association with the development and progression of diseases make it an important target for research and development. Further research is needed to fully understand the role of ZNF416 in cellular processes and its potential as a drug target and biomarker.
Protein Name: Zinc Finger Protein 416
Functions: May be involved in transcriptional regulation
The "ZNF416 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ZNF416 comprehensively, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
More Common Targets
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