Target Name: ZNF415
NCBI ID: G55786
Review Report on ZNF415 Target / Biomarker Content of Review Report on ZNF415 Target / Biomarker
ZNF415
Other Name(s): Zinc finger protein 415 (isoform 1) | ZNF415 variant 1 | FLJ11191 | zinc finger protein 415 | Pact | ZN415_HUMAN | ZfLp | Zinc finger protein 415, transcript variant 1 | Zinc finger protein 415

ZNF415: A Potential Drug Target and Biomarker

Zinc finger proteins (ZFPs) are a family of transmembrane proteins that play a crucial role in various cellular processes, including gene regulation, DNA replication, and cell signaling. ZNF415, also known as Zinc finger protein 415 (isoform 1), is a ZFP that is expressed in various tissues and cells, including neurons, astrocytes, and epithelial cells. Its unique structure and function make it an attractive candidate as a drug target or biomarker.

The ZNF415 gene, which encodes a protein of 214 amino acids, is located on chromosome 6p21. ZNF415 is a member of the ZNF gene family, which includes 14 other proteins, including ZNF1, ZNF2, ZNF3, ZNF4, ZNF5, ZNF6, ZNF7, ZNF8, ZNF9, ZNF10, ZNF11, ZNF12, and ZNF13. These genes are involved in various cellular processes, including cell growth, differentiation, and programmed cell death.

ZNF415 is expressed in various tissues and cells, including neurons, astrocytes, and epithelial cells. It is highly expressed in the brain, where it is predominantly expressed in the frontal cortical cortical layers. ZNF415 is also expressed in other tissues, including the heart, skeletal muscles, liver, and kidney.

The unique structure of ZNF415 makes it an attractive candidate as a drug target or biomarker. ZNF415 has a characteristic ZNF-like domain, which is composed of a series of conserved amino acids that are involved in protein-protein interactions. The ZNF-like domain is responsible for the protein's stability and functions as a dimer.

In addition to its unique structure, ZNF415 has several potential biomarker properties. For example, it has been shown to be involved in various signaling pathways, including the Wnt signaling pathway, the TGF-β signaling pathway, and the NF-kappa-B signaling pathway. ZNF415 has also been shown to play a role in cell signaling and has been linked to various cellular processes, including cell growth, differentiation, and programmed cell death.

ZNF415 has also been shown to be involved in the development and progression of various diseases, including cancer. For example, studies have shown that high levels of ZNF415 are associated with poor prognosis in various cancers, including breast, ovarian, and colorectal cancers. Additionally, ZNF415 has been shown to be involved in the regulation of cellular processes that are critical for cancer cell survival, such as the angiogenic switch and the maintenance of stem cell self-renewal.

Due to its unique structure and potential biomarker properties, ZNF415 is an attractive candidate as a drug target. Studies have shown that inhibiting ZNF415 can lead to a variety of cellular and molecular changes, including increased cell death, decreased cell proliferation, and altered cellular signaling pathways. Additionally, ZNF415 has been shown to play a role in the development of various diseases, including cancer, which makes it an attractive target for drug development.

In conclusion, ZNF415 is an attractive candidate as a drug target or biomarker due to its unique structure and function. Its potential as a drug target is further supported by its involvement in various signaling pathways and its association with the development of various diseases. Further research is needed to fully understand the role of ZNF415 in cellular processes and its potential as a drug target or biomarker.

Protein Name: Zinc Finger Protein 415

Functions: Involved in transcriptional regulation. Transcriptional activity differed among the various isoforms. All isoforms except isoform 3 seem to suppresses the transcriptional activities of AP-1 and p53/TP53

The "ZNF415 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ZNF415 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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