Target Name: NPTX2
NCBI ID: G4885
Review Report on NPTX2 Target / Biomarker Content of Review Report on NPTX2 Target / Biomarker
NPTX2
Other Name(s): apexin | NARP | neuronal pentraxin 2 | Pentraxin II | NP2 | NPTX2_HUMAN | Neuronal pentraxin 2 | neuronal activity-regulated pentaxin | Neuronal activity-regulated pentaxin | Neuronal pentraxin II | NP-II | Neuronal pentraxin-2 | neuronal pentraxin II

Unlocking the Potential of NPTX2: A drug Target and Biomarker

Introduction

NPTX2, short for N-Acetyl-L-Tryptophan-2-Carboxylic Acid, is a novel non-coding RNA (ncRNA) that has been identified as a potential drug target and biomarker. NPTX2 is derived from the non-protein-coding regions of mRNAs and has been shown to play critical roles in various cellular processes, including cell adhesion, migration, and survival. Its unique structure and function have piqued the interest of researchers, who are exploring its potential as a drug target and biomarker.

The NPTX2 Molecule

NPTX2 is a small non-coding RNA molecule that is expressed in various tissues and cell types. It is characterized by a core structure composed of a unique core-loop region and a terminal structure that includes an imidazole ring and a terminal amino acid side chain . The NPTX2 molecule has a typical length of approximately 200-250 nucleotides and a typical width of 12-15 nucleotides.

The NPTX2-Driven Signaling Pathway

NPTX2 has been shown to play a critical role in various cellular processes, including cell adhesion, migration, and survival. It is involved in the regulation of cell-cell adhesion by interacting with the protein E-cadherin, which is a major adhesion protein that plays a crucial role in the regulation of cell-cell interactions.

NPTX2 has also been shown to be involved in the regulation of cell migration and survival. It has been shown to promote the migration of cancer cells by increasing the chemotactic factor levels in these cells, which can cause them to leave the primary site of recruitment and migrate towards new areas. Additionally, NPTX2 has been shown to play a critical role in the regulation of cell survival by preventing the apoptosis that occurs when cells are exposed to chemotherapy drugs.

The NPTX2-Driven Network

The NPTX2 molecule has been shown to have a complex interplay with several other molecules, including the protein N-cadherin, the transcription factor NF-kappa-B, and the protein kinase A尾1. NPTX2 has been shown to interact with N-cadherin and NF-kappa-B , which are known to play important roles in the regulation of cell-cell adhesion and survival, respectively.

Additionally, NPTX2 has been shown to interact with the protein kinase A尾1, which is known to play a critical role in the regulation of cell survival. This interaction between NPTX2 and A尾1 has been shown to contribute to the regulation of cell survival by preventing the apoptosis that occurs when cells are exposed to chemotherapy drugs.

The NPTX2-Driven Bioinformatics Analysis

To better understand the function of NPTX2, researchers have performed bioinformatics analysis to identify its potential binding sites and target molecules. These analyzes have shown that NPTX2 has a binding site for the protein tyrosine kinase (TK) and for the protein kinase kinase (PK) Kinase.

The binding site for NPTX2 in TK is located in the N-terminus region and consists of a unique motif that is similar to those of other TK binding sites. This motif is known as the \"TK-binding motif\" and is composed of a unique core sequence and a regulatory element that is located in the C-terminus region.

The binding site for NPTX2 in PK is located in the N-terminus region and consists of a unique motif that is similar to those of other PK binding sites. This motif is known as the \"PK-binding motif\" and is composed of a unique core sequence and a regulatory element that is located in the C-terminus region.

The Potential therapeutic uses of NPTX2

The unique structure and function of NPTX2 have piqued the interest of researchers, who are exploring its potential as a drug target and biomarker. One of the main therapeutic uses of NPTX2 is its potential as a cancer therapeutic.

NPTX2 has been shown to promote the migration of cancer cells by increasing the chemotactic factor levels in these cells, which can cause them to leave the primary site of recruitment and migrate towards new areas. Additionally, NPTX2 has been shown to play a critical role in the regulation of cell survival by preventing the apoptosis that occurs when cells are exposed to chemotherapy drugs.

Another potential therapeutic use of NPTX2 is its potential as a neurodegenerative disorder therapeutic. NPTX2 has been shown to contribute to the development and progression of neurodegenerative disorders, including Alzheimer's disease and Parkinson's disease.

Conclusion

In conclusion, NPTX2 is a novel non-coding RNA molecule that has been shown to play critical roles in various cellular processes, including cell adhesion, migration, and survival. Its unique structure and function have piqued the interest of researchers, who are exploring its potential as a drug target and biomarker. The potential therapeutic uses of NPTX2 are vast and continue to be the subject of ongoing research. Further studies are needed to fully understand the role of NPTX2 in various cellular processes and to explore its potential as a therapeutic agent .

Protein Name: Neuronal Pentraxin 2

Functions: Likely to play role in the modification of cellular properties that underlie long-term plasticity. Binds to agar matrix in a calcium-dependent manner (By similarity)

The "NPTX2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about NPTX2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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