PDGFA: A Protein Targeted for Cancer and Inflammation (G5154)

Target Name: PDGFA

NCBI ID: G5154

PDGFA

PDGFA: A Protein Targeted for Cancer and Inflammation

PDGFA (Proteasome-Driven Generation of Glycoproteins) is a protein that plays a crucial role in the regulation of protein homeostasis in the body. It is a 26-kDa protein that is composed of two subunits, alpha and beta, that are held together by a disulfide bond. PDGFA is involved in the degradation of various proteins, including duplicated and aberrant proteins, as well as proteins that have reached the end of their lifespan.

PDGFA has been shown to be involved in a number of cellular processes, including cell growth, differentiation, and apoptosis. It has also been shown to play a role in the development and progression of various diseases, including cancer. As a result, PDGFA has become a target of interest for researchers looking for new treatments for these diseases.

One way that PDGFA has been targeted for drug development is as a potential therapeutic target for cancer. PDGFA has been shown to be involved in the regulation of cell division and has been linked to the development of various types of cancer. For example, studies have shown that high levels of PDGFA are associated with the development of breast cancer. Additionally, PDGFA has been shown to play a role in the development of lung cancer and has been shown to be involved in the regulation of cell apoptosis in these diseases.

Another way that PDGFA has been targeted for drug development is as a potential biomarker for cancer. PDGFA has been shown to be expressed in a variety of cancer types, including breast, lung, and ovarian cancer. Additionally, studies have shown that PDGFA levels are often elevated in the blood or lymph fluid of patients with cancer. As a result, PDGFA has been suggested as a potential biomarker for cancer and may be used in the development of new diagnostic tests for cancer.

PDGFA has also been targeted for drug development due to its potential role in the regulation of inflammation. PDGFA has been shown to be involved in the regulation of inflammation and has been linked to the development of various inflammatory diseases. For example, studies have shown that PDGFA is involved in the regulation of the production of pro-inflammatory cytokines. Additionally, PDGFA has been shown to play a role in the regulation of the production of anti-inflammatory cytokines.

In addition to its potential role in cancer and inflammation, PDGFA has also been shown to have a number of other potential functions in the body. For example, PDGFA has been shown to play a role in the regulation of cell signaling and has been linked to the development of various neurodegenerative diseases. Additionally, PDGFA has been shown to play a role in the regulation of cell adhesion and has been linked to the development of various diseases, including cancer.

Overall, PDGFA is a protein that has a number of potential functions in the body and has been shown to be involved in a variety of cellular processes. As a result, PDGFA has become a target of interest for researchers looking for new treatments for various diseases. Further research is needed to fully understand the role of PDGFA in the regulation of protein homeostasis and to develop new treatments for the diseases that are associated with its dysfunction.

Protein Name: Platelet Derived Growth Factor Subunit A

Functions: Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal lung alveolar septum formation during embryogenesis, normal development of the gastrointestinal tract, normal development of Leydig cells and spermatogenesis. Required for normal oligodendrocyte development and normal myelination in the spinal cord and cerebellum. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFB (By similarity)

The "PDGFA Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PDGFA comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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