Target Name: PLP2
NCBI ID: G5355
Review Report on PLP2 Target / Biomarker Content of Review Report on PLP2 Target / Biomarker
PLP2
Other Name(s): A4 differentiation-dependent protein | differentiation-dependent protein A4 | Intestinal membrane A4 protein | PLP2_HUMAN | proteolipid protein 2 (colonic epithelium-enriched) | MGC126187 | A4 | proteolipid protein 2 | intestinal membrane A4 protein | Differentiation-dependent protein A4 | Proteolipid protein 2 | A4LSB

PLP2: A Drug Target / Disease Biomarker

PLP2, also known as protamine phosphate synthase 2, is a protein that is expressed in various tissues throughout the body. It is a key enzyme in the synthesis of a group of proteins known as the protamines, which are involved in a variety of cellular processes. PLP2 has also been shown to play a role in the regulation of cellular signaling pathways, and is potential drug target for various diseases.

The protamines are a group of small proteins that contain a characteristic domain known as a nucleotide-binding oligomerization (NBO) domain. These proteins are involved in a variety of cellular processes, including cell signaling, DNA replication, and metabolism. PLP2 is a key enzyme in the synthesis of these protamines, and is responsible for the production of the most abundant protamine, known as protamine phosphate.

PLP2 is a key enzyme in the synthesis of the protamine phosphate, which is a key signaling molecule in the regulation of cellular signaling pathways. It is part of a complex that is involved in the regulation of the level of a protein called NF-kappa-B, which is a transcription factor that plays a role in the regulation of cellular processes such as cell signaling, inflammation, and metabolism.

Studies have shown that PLP2 plays a critical role in the regulation of NF-kappa-B activity, and that it is involved in the inhibition of NF-kappa-B-mediated signaling pathways. This is important because NF-kappa-B is involved in the regulation of many cellular processes, including cell signaling, inflammation, and survival.

PLP2 is also involved in the regulation of cellular apoptosis, which is the process by which cells die when they are no longer needed. Studies have shown that PLP2 plays a critical role in the regulation of apoptosis, and that it is involved in the inhibition of pro-apoptotic signaling pathways. This is important because apoptosis is a natural and necessary process for the development and maintenance of tissues and organs, and it is important for the regulation of cellular processes such as cell signaling and stress responses.

PLP2 is also involved in the regulation of cellular aging, which is the process by which cells become less functional and more susceptible to damage and disease. Studies have shown that PLP2 plays a critical role in the regulation of cellular aging, and that it is involved in the inhibition of processes that contribute to cellular aging. This is important because cellular aging is a key factor in the development and progression of many diseases, including cancer, neurodegenerative diseases, and cardiovascular diseases.

In conclusion, PLP2 is a key protein that is involved in the regulation of various cellular processes, including cell signaling, DNA replication, and metabolism. It is also involved in the production of the protamine phosphate, which is a key signaling molecule in the regulation of cellular signaling pathways. PLP2 plays a critical role in the regulation of NF-kappa-B activity, cellular apoptosis, and cellular aging, and is potential drug target for various diseases. Further research is needed to fully understand the role of PLP2 in cellular processes and its potential as a drug target.

Protein Name: Proteolipid Protein 2

Functions: May play a role in cell differentiation in the intestinal epithelium

The "PLP2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PLP2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

PLPBP | PLPP1 | PLPP2 | PLPP3 | PLPP4 | PLPP5 | PLPP6 | PLPP7 | PLPPR1 | PLPPR2 | PLPPR3 | PLPPR4 | PLPPR5 | PLPPR5-AS1 | PLRG1 | PLS1 | PLS3 | PLSCR1 | PLSCR2 | PLSCR3 | PLSCR4 | PLSCR5 | PLTP | PLUT | PLVAP | PLXDC1 | PLXDC2 | PLXNA1 | PLXNA2 | PLXNA3 | PLXNA4 | PLXNB1 | PLXNB2 | PLXNB3 | PLXNC1 | PLXND1 | PM20D1 | PM20D2 | PMAIP1 | PMCH | PMCHL1 | PMCHL2 | PMEL | PMEPA1 | PMF1 | PMF1-BGLAP | PMFBP1 | PML | PMM1 | PMM2 | PMP2 | PMP22 | PMPCA | PMPCB | PMS1 | PMS2 | PMS2P1 | PMS2P12 | PMS2P13 | PMS2P2 | PMS2P3 | PMS2P4 | PMS2P5 | PMS2P9 | PMVK | PNCK | PNISR | PNISR-AS1 | PNKD | PNKP | PNKY | PNLDC1 | PNLIP | PNLIPRP1 | PNLIPRP2 | PNLIPRP3 | PNMA1 | PNMA2 | PNMA3 | PNMA5 | PNMA6A | PNMA8A | PNMA8B | PNMT | PNN | PNO1 | PNOC | PNP | PNPLA1 | PNPLA2 | PNPLA3 | PNPLA4 | PNPLA5 | PNPLA6 | PNPLA7 | PNPLA8 | PNPO | PNPT1 | PNRC1 | PNRC2