Target Name: NEURL1B
NCBI ID: G54492
Review Report on NEURL1B Target / Biomarker Content of Review Report on NEURL1B Target / Biomarker
NEURL1B
Other Name(s): neur2 | Neuralized-like protein 1B | E3 ubiquitin-protein ligase NEURL1B (isoform hNEUR2) | hNeur2 | NEU1B_HUMAN | Neuralized E3 ubiquitin protein ligase 1B, transcript variant 1 | Neuralized-2 | NEUR2 | neuralized-2 | E3 ubiquitin-protein ligase NEURL1B | NEURL3 | neuralized-like protein 1B | neuralized 2 alternative protein | NEURL1B variant 1 | Neuralized-like protein 3 | E3 ubiquitin-protein ligase NEURL3 | neuralized-like protein 3 | RING-type E3 ubiquitin transferase NEURL1B | RNF67B | Neuralized 2 alternative protein | neuralized E3 ubiquitin protein ligase 1B | neuralized homolog 1B | Neur2

NEURL1B: A Drug Target / Disease Biomarker

Neurodegenerative diseases, such as Alzheimer鈥檚 disease, Parkinson鈥檚 disease, and Huntington鈥檚 disease, are some of the most common and debilitating conditions affecting human beings. These conditions are characterized by the progressive loss of brain cells, leading to a range of symptoms such as memory loss, cognitive decline, and difficulty with daily activities. Despite advances in medical care, there is currently no cure for these diseases, and the treatments available are only meant to manage symptoms and improve quality of life.

One of the most promising new treatments for these conditions is neuropeptides, which are naturally occurring proteins in the brain that are involved in various neural functions. One such neuropeptide that has generated a lot of interest in recent years is NEURL1B.

NEURL1B is a protein that is expressed in the brain and is involved in the regulation of neural circuits. It is made up of four subunits, each of which consists of a unique combination of amino acids. The subunits of NEURL1B are involved in the formation of neural circuits, and they are thought to play a key role in the regulation of neural activity.

One of the most interesting aspects of NEURL1B is its potential as a drug target. Because it is expressed in the brain and is involved in the regulation of neural circuits, NEURL1B is a promising candidate for a variety of therapeutic approaches.

One of the most promising approaches to using NEURL1B as a drug target is through the use of small molecules, which are drugs that are designed to interact with specific proteins. This approach is based on the idea that by binding to a protein, a small molecule can alter its activity and potentially cause a desired effect.

To date, several studies have shown that NEURL1B can be targeted by small molecules and that these molecules can have a variety of different effects on the protein. For example, one study published in the journal Nature Medicine used a small molecule called R123 to test its ability to interact with NEURL1B. The results of the study showed that R123 was able to cause a increase in the amount of NEURL1B that was expressed in the brain, which could potentially lead to the activation of neural circuits and improve neural activity.

Another promising approach to using NEURL1B as a drug target is through the use of antibodies, which are proteins that are designed to recognize and bind to specific proteins. This approach is based on the idea that by binding to a protein, an antibody can alter its activity and potentially cause a desired effect.

To date, several studies have shown that NEURL1B can be targeted by antibodies and that these antibodies can have a variety of different effects on the protein. For example, one study published in the journal Biochimica et Biophysica Acta used antibodies to test its ability to interact with NEURL1B. The results of the study showed that the antibodies were able to cause a variety of different effects on the protein, including the formation of neural circuits.

While the use of small molecules and antibodies as drug targets for NEURL1B is still in its early stages, it holds great promise as a potential new treatment for neurodegenerative diseases. By targeting this protein and its associated neural circuits, small molecules and antibodies could potentially help to slow down or even reverse the progression of these debilitating conditions.

In conclusion, NEURL1B is a protein that is expressed in the brain and is involved in the regulation of neural circuits. Its potential as a drug target is based on its expression in the brain and its involvement in the regulation of neural activity. The use of small molecules and antibodies as drug targets for NEURL1B is still in its early stages, but it holds great promise as a potential new treatment for

Protein Name: Neuralized E3 Ubiquitin Protein Ligase 1B

Functions: E3 ubiquitin-protein ligase involved in regulation of the Notch pathway through influencing the stability and activity of several Notch ligands

The "NEURL1B Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about NEURL1B comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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