TRPM7: A Drug Target / Disease Biomarker (G54822)

Target Name: TRPM7

NCBI ID: G54822

TRPM7

TRPM7: A Drug Target / Disease Biomarker

TRPM7 is a protein that is expressed in various tissues and cells in the body. It is a member of the TRP family of cytoplasmic proteinases, which are known for their ability to regulate cellular processes such as cell adhesion, migration, and apoptosis.

One of the unique features of TRPM7 is its ability to interact with various signaling molecules, including TGF-β, NF-kappa-B, and MAPK. This interaction with these signaling molecules has led to the conclusion that TRPM7 may be involved in the regulation of cellular processes that are important for tissue repair and regeneration.

In addition to its role in signaling pathways, TRPM7 has also been shown to play a role in the regulation of pain perception. Studies have shown that TRPM7 is involved in the regulation of pain signaling pathways, and that its activity may be modulated by drugs that are used to treat pain.

Despite these promising findings, much work remains to be done in order to fully understand the role of TRPM7 in cellular processes. One of the major challenges in studying TRPM7 is its expression and function, as the molecule is difficult to purify and manipulate. Additionally, the precise mechanisms by which TRPM7 functions in cellular processes are not well understood, and further research is needed to determine its role in these processes.

In conclusion, TRPM7 is a protein that has the potential to be a drug target or biomarker. Its unique ability to interact with various signaling molecules and its involvement in the regulation of pain perception make it an attractive candidate for further study. Further research is needed to fully understand its role in cellular processes and its potential as a drug target.

Protein Name: Transient Receptor Potential Cation Channel Subfamily M Member 7

Functions: Essential ion channel and serine/threonine-protein kinase. Divalent cation channel permeable to calcium and magnesium (PubMed:35561741). Has a central role in magnesium ion homeostasis and in the regulation of anoxic neuronal cell death. Involved in TNF-induced necroptosis downstream of MLKL by mediating calcium influx. The kinase activity is essential for the channel function. May be involved in a fundamental process that adjusts plasma membrane divalent cation fluxes according to the metabolic state of the cell. Phosphorylates annexin A1 (ANXA1)

The "TRPM7 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about TRPM7 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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