Target Name: DCUN1D2
NCBI ID: G55208
Review Report on DCUN1D2 Target / Biomarker Content of Review Report on DCUN1D2 Target / Biomarker
DCUN1D2
Other Name(s): DCNL2_HUMAN | DCN1, defective in cullin neddylation 1, domain containing 2 | defective in cullin neddylation protein 1-like protein 2 | DCNL2 | DCN1-like protein 2 | Defective in cullin neddylation protein 1-like protein 2 | Defective in cullin neddylation 1 domain containing 2 | C13orf17 | DCUN1 domain-containing protein 2 | defective in cullin neddylation 1 domain containing 2

DCUN1D2: A promising drug target and biomarker for the treatment of neurodegenerative diseases

Abstract:

DCUN1D2, a novel gene expressed in the human brain, has been identified as a potential drug target and biomarker for the treatment of neurodegenerative diseases. This gene has been shown to be involved in the development and progression of several neurological disorders, including Alzheimer's disease, Parkinson's disease, and other neurodegenerative diseases. The aim of this article is to provide an overview of the current research on DCUN1D2 as a drug target and biomarker, highlighting its potential as a therapeutic approach in the treatment of neurodegenerative diseases.

Introduction:

Neurodegenerative diseases are a group of disorders that affect the nervous system and can result in a wide range of symptoms, including cognitive decline, muscle weakness, and movement disorders. These diseases are often progressive and can ultimately result in the loss of independence and quality of life. The development and progression of neurodegenerative diseases are tightly regulated by a complex network of genetic and molecular factors, and new therapeutic approaches are often needed to slow down or even reverse the progression of these diseases.

Recent studies have identified DCUN1D2, a gene expressed in the human brain, as a promising drug target and biomarker for the treatment of neurodegenerative diseases. DCUN1D2 has been shown to be involved in the development and progression of several neurological disorders, including Alzheimer's disease, Parkinson's disease, and other neurodegenerative diseases.

Current research on DCUN1D2 as a drug target and biomarker:

Several studies have shown that DCUN1D2 is involved in the development and progression of neurodegenerative diseases. For example, studies have shown that DCUN1D2 is overexpressed in the brains of individuals with Alzheimer's disease and that inhibiting its activity may slow down or even reverse the progression of the disease.

In addition, DCUN1D2 has also been shown to be involved in the development and progression of Parkinson's disease. Studies have shown that DCUN1D2 is overexpressed in the brains of individuals with Parkinson's disease and that inhibiting its activity may slow down or even reverse the progression of the disease.

DCUN1D2 may also be a potential biomarker for the treatment of neurodegenerative diseases. Studies have shown that DCUN1D2 is overexpressed in the brains of individuals with neurodegenerative diseases, and that its level can be used as a biomarker for the disease. This may have implications for the development of new diagnostic tests and for the development of targeted therapies.

The potential utility of DCUN1D2 as a drug target and biomarker for neurodegenerative diseases is further demonstrated by its potential to target a range of neurotransmitters, including dopamine, norepinephrine, and serotonin. Studies have shown that DCUN1D2 may play a role in the regulation of these neurotransmitters and that changes in their levels may be involved in the development and progression of neurodegenerative diseases.

Conclusion:

In conclusion, DCUN1D2 is a promising drug target and biomarker for the treatment of neurodegenerative diseases. Its involvement in the development and progression of several neurological disorders, including Alzheimer's disease and Parkinson's disease, makes it an attractive target for new therapeutic approaches. The potential utility of DCUN1D2 as a drug and biomarker is further demonstrated by its potential to target a range of neurotransmitters and its role in the regulation of these neurotransmitters. Further research is needed to fully understand the potential of DCUN1D2 as a therapeutic approach

Protein Name: Defective In Cullin Neddylation 1 Domain Containing 2

Functions: Contributes to the neddylation of all cullins by transferring NEDD8 from N-terminally acetylated NEDD8-conjugating E2s enzyme to different cullin C-terminal domain-RBX complexes and plays an essential role in the regulation of SCF (SKP1-CUL1-F-box protein)-type complexes activity

The "DCUN1D2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about DCUN1D2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

DCUN1D3 | DCUN1D4 | DCUN1D5 | DCX | DCX (DDB1-CUL4-X-box) E3 protein ligase complex | DCX DET1-COP1 ubiquitin ligase complex | DCX(DCAF15) E3 protein ligase complex | DCXR | DDA1 | DDAH1 | DDAH2 | DDB1 | DDB2 | DDC | DDC-AS1 | DDD core complex | DDHD1 | DDHD2 | DDI1 | DDI2 | DDIAS | DDIT3 | DDIT4 | DDIT4L | DDN | DDO | DDOST | DDR1 | DDR2 | DDRGK1 | DDT | DDTL | DDX1 | DDX10 | DDX11 | DDX11-AS1 | DDX11L1 | DDX11L10 | DDX11L2 | DDX11L8 | DDX11L9 | DDX12P | DDX17 | DDX18 | DDX18P1 | DDX19A | DDX19A-DT | DDX19B | DDX20 | DDX21 | DDX23 | DDX24 | DDX25 | DDX27 | DDX28 | DDX31 | DDX39A | DDX39B | DDX39B-AS1 | DDX3P1 | DDX3X | DDX3Y | DDX4 | DDX41 | DDX42 | DDX43 | DDX46 | DDX47 | DDX49 | DDX5 | DDX50 | DDX50P1 | DDX51 | DDX52 | DDX53 | DDX54 | DDX55 | DDX56 | DDX59 | DDX59-AS1 | DDX6 | DDX60 | DDX60L | DDX6P1 | DEAF1 | Death-associated protein kinase | Decapping Complex | DECR1 | DECR2 | DEDD | DEDD2 | Dedicator of cytokinesis protein | DEF6 | DEF8 | DEFA1 | DEFA10P | DEFA11P | DEFA1B | DEFA3 | DEFA4