PPP1R9A: A Potential Drug Target and Biomarker for Proteasome-Mediated Signaling

Target Name: PPP1R9A

NCBI ID: G55607

PPP1R9A

PPP1R9A: A Potential Drug Target and Biomarker for Proteasome-Mediated Signaling

Proteasome-mediated signaling is a complex cellular signaling pathway that plays a crucial role in regulating various cellular processes, including cell growth, apoptosis, and metabolism. The protein phosphatase 1 (PP1) is a key regulator of proteasome-mediated signaling, and its subunit, PPP1R9A, has been identified as a potential drug target and biomarker.

In this article, we will provide an overview of PPP1R9A, its function in proteasome-mediated signaling, its potential as a drug target, and its potential as a biomarker for various diseases.

Function and Localization

PP1 is a 26 kDa protein that is predominantly localized to the endoplasmic reticulum (ER) and nuclear envelope (NE). It is involved in the regulation of protein translation, and its activity can be inhibited by various chemical or biological factors. PPP1R9A is a 21 kDa protein that is predominantly localized to the cytoplasm (endoplasmic reticulum (ER), and nuclear envelope (NE). It is involved in the regulation of protein translation, and its activity can be inhibited by various chemical or biological factors.

PP1R9A functions as a protein phosphatase by removing the phosphate groups from the active sites of other proteins. This process is critical for the regulation of protein function and cell signaling. PPP1R9A is involved in the regulation of various cellular processes, including cell growth, apoptosis, and metabolism.

PP1R9A is also involved in the regulation of gene expression. It has been shown to play a role in the regulation of cell adhesion, cell-cell signaling, and cell proliferation. Additionally, PPP1R9A is involved in the regulation of inflammation, as it has been shown to play a role in the regulation of immune cell function and the production of pro-inflammatory cytokines.

Potential Drug Target

PPP1R9A has been identified as a potential drug target due to its involvement in the regulation of protein translation and its role in the regulation of gene expression. Drugs that target PPP1R9A have the potential to inhibit its function as a regulator of protein translation and cell signaling, leading to the inhibition of cellular processes that are associated with various diseases, such as cancer, neurodegenerative diseases, and autoimmune diseases.

In addition, PPP1R9A has been shown to play a role in the regulation of inflammation, as it has been shown to play a role in the regulation of immune cell function and the production of pro-inflammatory cytokines. Drugs that target PPP1R9A have the potential to inhibit its function in the regulation of inflammation and may be effective in treating various inflammatory diseases.

Biomarker Potential

PPP1R9A has been identified as a potential biomarker for various diseases due to its involvement in the regulation of protein translation and its role in the regulation of gene expression. The levels of PPP1R9A have been shown to be affected by various diseases, including cancer, neurodegenerative diseases, and autoimmune diseases.

In addition, PPP1R9A has been shown to play a role in the regulation of inflammation, as it has been shown to play a role in the regulation of immune cell function and the production of pro-inflammatory cytokines. The levels of PPP1R9A have been shown to be affected by various inflammatory diseases, including cancer, neurodegenerative diseases, and autoimmune diseases.

Conclusion

In conclusion, PPP1R9A is a protein that is involved in the regulation of protein translation and cell signaling, as well as the regulation of gene expression and inflammation. Its function as a regulator of protein translation and its involvement in the regulation of gene expression and inflammation make it a potential drug target and biomarker for various diseases. Further research is needed to fully understand the role of PPP1R9A in cellular signaling and its potential as a drug target and biomarker.

Protein Name: Protein Phosphatase 1 Regulatory Subunit 9A

Functions: Binds to actin filaments (F-actin) and shows cross-linking activity. Binds along the sides of the F-actin. May be involved in neurite formation. Inhibits protein phosphatase 1-alpha activity (By similarity)

The "PPP1R9A Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PPP1R9A comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
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•   related combination drugs;
•   pharmacochemistry experiments;
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•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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