CENPH: A Potential Drug Target Or Biomarker (G64946)

Target Name: CENPH

NCBI ID: G64946

CENPH

CENPH: A Potential Drug Target Or Biomarker

CENPH (CENPH-HUMAN) is a protein that is expressed in human tissues and has been identified as a potential drug target or biomarker. It is a member of the ENPH (endoplasmic reticulum-associated protein) family, which is known for its role in regulating protein synthesis and quality control in the endoplasmic reticulum.

CENPH is a 120 amino acid protein that is expressed in various human tissues, including the brain, heart, liver, and pancreas. It is typically produced in the endoplasmic reticulum, where it can interact with various proteins that are involved in protein synthesis and modification.

One of the key functions of CENPH is its role in regulating the stability of proteins that are synthesized in the endoplasmic reticulum. This is done by helping to ensure that these proteins are properly folded and translated into their correct forms, and by preventing their degradation or misfolding.

CENPH has also been shown to play a role in the regulation of cellular signaling pathways. For example, it has been shown to interact with the protein kinase ALCAT, which is involved in the regulation of cell signaling pathways that are important for various cellular processes, including cell growth, differentiation, and survival.

In addition to its role in regulating protein synthesis and signaling pathways, CENPH has also been shown to be involved in the regulation of cellular stress responses. This is done by helping to ensure that cells are able to respond properly to stressors, such as changes in temperature, pH, or the availability of oxygen and nutrients.

Given its role in regulating protein synthesis and signaling pathways, CENPH is a potential drug target or biomarker that could be targeted by small molecules or other therapeutic agents. For example, studies have shown that CENPH can be targeted by small molecules that are able to modulate its activity, such as inhibitors of the protein kinase ALCAT.

In addition to its potential as a drug target or biomarker, CENPH is also of interest as a potential therapeutic agent for a variety of diseases. For example, studies have shown that CENPH is involved in the regulation of cellular stress responses, which could make it a useful target for treatments that are aimed at improving cellular stress resilience.

In addition to its potential therapeutic applications, CENPH is also of interest as a potential research tool. Because it is expressed in a variety of human tissues, it can be used as a cell culture model for the study of protein synthesis and signaling pathways. This can be done by using techniques such as Western blotting or immunofluorescence to detect and quantify the expression of CENPH in different tissues.

Overall, CENPH is a protein that has the potential to be a drug target or biomarker, as well as a valuable tool for the study of protein synthesis and signaling pathways. Further research is needed to fully understand its role in these processes and to determine its potential as a therapeutic agent.

Protein Name: Centromere Protein H

Functions: Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. Required for chromosome congression and efficiently align the chromosomes on a metaphase plate

The "CENPH Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CENPH comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets