CENPO: A Potential Drug Target and Biomarker (G79172)

Target Name: CENPO

NCBI ID: G79172

CENPO

CENPO: A Potential Drug Target and Biomarker

CENPO (CENPO_HUMAN), also known as human centromean protein, is a protein that is expressed in the human body and is found in most tissues. It is a key component of the cytoskeleton and plays a role in the structure and function of cells.

Recent studies have identified CENPO as a potential drug target and biomarker for a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. This is due to its unique structure, which allows it to interact with a variety of molecules, as well as its involvement in several cellular processes that are relevant to many diseases.

One of the key features of CENPO is its cytoskeleton-associated protein (CAP) domain. This domain is present in the majority of CENPO isoforms and is responsible for its cytoskeleton-associated properties. The CAP domain is involved in the regulation of cell shape, as well as the assembly and disassembly of the cytoskeleton.

In addition to its role in the cytoskeleton, CENPO is also involved in several signaling pathways that are relevant to many diseases. For example, it has been shown to be involved in the regulation of cell proliferation and has been implicated in the development of cancer.

Another feature of CENPO is its ability to interact with a variety of molecules, including transcription factors, cytokines, and signaling proteins. This allows CENPO to play a role in the regulation of cellular processes that are relevant to many diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

CENPO is also a potential biomarker for a variety of diseases due to its expression in a wide range of tissues and its ability to be easily isolated from these tissues. This makes it a promising target for diagnostic studies and the development of biomarkers for a variety of diseases.

In conclusion, CENPO is a protein that has been identified as a potential drug target and biomarker for a variety of diseases due to its unique structure and involvement in several cellular processes that are relevant to many diseases. Further research is needed to fully understand its role in these processes and its potential as a drug and biomarker.

Protein Name: Centromere Protein O

Functions: Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Modulates the kinetochore-bound levels of NDC80 complex

The "CENPO Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CENPO comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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