A Promising Lead for Drug Development: Multifunctional Protein CAD as a Potential Target or Biomarker

Target Name: CAD

NCBI ID: G790

Content of Review Report on CAD Target / Biomarker

CAD

A Promising Lead for Drug Development: Multifunctional Protein CAD as a Potential Target or Biomarker

CAD (Cadherin-associated protein) is a transmembrane protein that plays a crucial role in cell-cell adhesion, vital signaling, and tissue repair. Among its various functions, CAD has been implicated in cancer progression and metastasis. As a result, CAD has emerged as a promising target for drug development, with a focus on inhibiting its functions potentially leading to the development of new treatments for various diseases. In this article, we will explore the multifunctional protein CAD as a drug target or biomarker and its potential in the development of new treatments.

The Protein cadherin

CAD is a member of the cadherin family, which is characterized by the presence of a transmembrane domain and a cytoplasmic tail. This family is involved in various physiological processes, including cell-cell adhesion, angiogenesis, and tissue repair. CAD is specifically involved in the regulation of cell-cell adhesion, which is a critical process that ensures the integrity of tissues and is essential for various physiological functions, such as embryonic development, tissue repair, and cancer progression.

In cancer progression, CAD has been implicated in the regulation of cell-cell adhesion, which allows cancer cells to stick together, migrate, and form tumors. Additionally, CAD has been shown to play a role in the development of various types of cancer, including breast, ovarian, and colorectal cancer.

As a drug target, CAD has the potential to be a valuable target for cancer treatment. By inhibiting the functions of CAD, researchers may be able to reduce the formation of new cancer cells and potentially slow down or even reverse the progression of existing cancer.

During the development of cancer, CAD can also contribute to the development of metastasis. By enabling cancer cells to migrate and stick together, CAD may help to facilitate the formation of tumors and the spread of cancer throughout the body.

The potential of CAD as a drug target is further underscored by the numerous studies that have demonstrated the effectiveness of inhibitors of CAD in various cancer types. For example, studies have shown that inhibitors of CAD can significantly reduce the growth of cancer cells in both in vitro and in vivo models. Additionally, several anti-cancer drugs that are currently in use, such as tamoxifen and taxol, have been shown to inhibit the functions of CAD.

As a biomarker, CAD may also be used as a diagnostic tool for cancer. The expression of CAD has been shown to be elevated in various types of cancer, including breast, ovarian, and colorectal cancer. Additionally, the level of CAD has been shown to be associated with the severity of certain types of cancer.

The multifunctional protein CAD

While CAD has been shown to be involved in various physiological processes, its functions are not yet fully understood. Several studies have demonstrated that CAD plays a role in cell-cell adhesion, angiogenesis, and the regulation of stem cell proliferation.

One of the most well-known functions of CAD is its role in cell-cell adhesion. cadherins are involved in the formation of tight junctions, which are a type of cell-cell adhesion that helps to maintain the integrity of tissues. Additionally, CAD has been shown to play a role in the regulation of cell-cell adhesion in various tissues, including brain, heart, and kidney.

Another function of CAD is its role in angiogenesis, the process by which new blood vessels are formed. CAD has been shown to play a role in the regulation of angiogenesis in various tissues, including cancer.

Additionally, CAD has also been shown to play a role in the regulation of stem cell proliferation. CAD has been shown to play a

Protein Name: Carbamoyl-phosphate Synthetase 2, Aspartate Transcarbamylase, And Dihydroorotase

Functions: This protein is a 'fusion' protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase)

The "CAD Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CAD comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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