Target Name: URM1
NCBI ID: G81605
Review Report on URM1 Target / Biomarker Content of Review Report on URM1 Target / Biomarker
URM1
Other Name(s): RP11-339B21.4 | ubiquitin-related modifier 1 homolog | URM1 variant 2 | URM1_HUMAN | C9orf74 | Ubiquitin related modifier 1, transcript variant 2 | Ubiquitin-related modifier 1 (isoform b) | ubiquitin related modifier 1 | Ubiquitin-related modifier 1

URM1: A Protein Involved in Cell Signaling and Cellular Processes

URM1 (RP11-339B21.4) is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the URM family of proteins, which are known for their role in cell signaling and division. URM1 has been shown to play a role in a variety of physiological processes, including cell growth, differentiation, and survival.

One of the unique features of URM1 is its ability to interact with other proteins. URM1 can form a complex with the protein p120GAP, which is a known regulator of the HSP70 gene. This complex plays a role in regulating the activity of p120GAP and in the regulation of cellular processes such as cell growth, differentiation, and survival.

URM1 has also been shown to interact with the proteinBeclin-1. Beclin-1 is a protein that is known to play a role in the regulation of cellular processes such as cell adhesion, migration, and invasion. URM1 can form a complex with Beclin- 1, which may influence the activity of Beclin-1 and the regulation of cellular processes.

In addition to its interactions with p120GAP and Beclin-1, URM1 has also been shown to interact with a variety of other proteins. URM1 can also form a complex with the proteinKLF1, which is a known regulator of gene expression. with the proteinSCL/TAL1, which is involved in the regulation of cellular processes such as cell growth, differentiation, and survival.

URM1 is also expressed in various tissues of the body, including the brain. It has been shown to play a role in the regulation of cellular processes in the brain, including the regulation of neurotransmitter release, cell growth, and survival.

In addition to its role in cellular processes, URM1 has also been shown to play a role in the regulation of cellular interactions with other cells. URM1 can form a complex with the proteinEts1, which is involved in the regulation of cellular interactions with neighboring cells. This complex may influence the activity of Ets1 and the regulation of cellular interactions with neighboring cells.

URM1 is also involved in the regulation of cellular processes in the kidney. It has been shown to play a role in the regulation of cellular processes in the kidney, including the regulation of water and electrolyte balance.

In conclusion, URM1 is a protein that is involved in a variety of cellular processes in the body. Its interactions with other proteins, including p120GAP, Beclin-1, KLF1, SCL/TAL1, and Ets1, have been shown to play a role in the regulation of cellular processes such as cell growth, differentiation, and survival. URM1 is also expressed in various tissues of the body, including the brain and kidneys, and has been shown to play a role in the regulation of cellular interactions with other cells. Further research is needed to fully understand the role of URM1 in cellular processes and its potential as a drug target or biomarker.

Protein Name: Ubiquitin Related Modifier 1

Functions: Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as MOCS3, ATPBD3, CTU2, USP15 and CAS. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates

The "URM1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about URM1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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