Target Name: USH1G
NCBI ID: G124590
Review Report on USH1G Target / Biomarker Content of Review Report on USH1G Target / Biomarker
USH1G
Other Name(s): USH1 protein network component sans | USH1 protein network component sans, transcript variant 1 | USH1G variant 1 | USH1G_HUMAN | SANS | Scaffold protein containing ankyrin repeats and SAM domain | pre-mRNA splicing regulator USH1G | FLJ33924 | ANKS4A | usher syndrome type-1G protein | Usher syndrome 1G (autosomal recessive) | Usher syndrome type-1G protein (isoform 1) | scaffold protein containing ankyrin repeats and SAM domain

USH1G: A Potential Drug Target and Biomarker for Neural Cell Communication

USH1G, also known as USH1 gene, is a protein that is expressed in various tissues of the brain, including the cerebral cortical cortical neurons, astrocytes, and glial cells. It is a member of the USH1 family of transmembrane proteins, which are known for their role in intracellular signaling. USH1G has been shown to play a role in neural cell communication and has potential as a drug target or biomarker.

The USH1G protein is involved in the formation of the axoninitial segment (AIS), which is the first portion of an axon that is released from a neuron and is involved in the formation of the myelin sheath that surrounds and supports neuronal fibers. The AIS is a critical structure that allows neurons to communicate with each other and to receive signals from other cells. USH1G is known to be involved in the regulation of the AIS formation and has been shown to play a role in the development and maintenance of neuronal communication.

In addition to its role in neural cell communication, USH1G has also been shown to play a role in the regulation of cell survival and metabolism. The USH1G gene has been shown to encode a protein that is involved in cell survival and has been shown to play a role in the regulation of cell proliferation and differentiation.

Furthermore, USH1G has been shown to be involved in the regulation of neural plasticity, which is the ability of the brain to change and adapt over time. Neural plasticity is critical for the development and maintenance of neural networks and is involved in a wide range of cognitive functions. USH1G has been shown to be involved in the regulation of neural plasticity and has been shown to play a role in the development of neurodegenerative diseases.

Despite its importance in neural cell communication and neural plasticity, USH1G is not yet a well-established drug target or biomarker. There is a need for further research to determine the full role of USH1G in neural signaling and to explore its potential as a drug or biomarker.

In conclusion, USH1G is a protein that is involved in various aspects of neural cell communication and has potential as a drug target or biomarker. Further research is needed to fully understand its role in neural signaling and to explore its potential as a drug or biomarker.

Protein Name: USH1 Protein Network Component Sans

Functions: Plays a role in pre-mRNA splicing by regulating the release and transfer of U4/U6.U5 tri-small nuclear ribonucleoprotein (tri-snRNP) complexes from their assembly site in Cajal bodies to nuclear speckles, thereby contributing to the assembly of the pre-catalytic spliceosome on target pre-mRNAs (PubMed:34023904). May also participate in recycling of snRNPs back to Cajal bodies during splicing (PubMed:34023904). Plays a role in regulating MAGI2-mediated endocytosis (PubMed:24608321). Anchoring/scaffolding protein that is a part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal development and maintenance of cochlear hair cell bundles. Required for normal hearing

The "USH1G Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about USH1G comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

USH2A | USHBP1 | USO1 | USP1 | USP1-UAF1 complex | USP10 | USP11 | USP12 | USP12-AS1 | USP12-DT | USP13 | USP14 | USP15 | USP16 | USP17L1 | USP17L10 | USP17L11 | USP17L12 | USP17L13 | USP17L14P | USP17L15 | USP17L17 | USP17L18 | USP17L2 | USP17L20 | USP17L21 | USP17L24 | USP17L25 | USP17L26 | USP17L27 | USP17L29 | USP17L3 | USP17L5 | USP17L6P | USP17L7 | USP17L8 | USP17L9P | USP18 | USP19 | USP2 | USP2-AS1 | USP20 | USP21 | USP22 | USP24 | USP25 | USP26 | USP27X | USP27X-DT | USP28 | USP29 | USP3 | USP3-AS1 | USP30 | USP30-AS1 | USP31 | USP32 | USP32P1 | USP32P2 | USP32P3 | USP33 | USP34 | USP35 | USP36 | USP37 | USP38 | USP39 | USP4 | USP40 | USP41 | USP42 | USP43 | USP44 | USP45 | USP46 | USP46-DT | USP47 | USP48 | USP49 | USP5 | USP50 | USP51 | USP53 | USP54 | USP6 | USP6NL | USP6NL intronic transcript 1 (non-protein coding), transcript variant 1 | USP7 | USP8 | USP8P1 | USP9X | USP9Y | USPL1 | UST | UTF1 | UTP11 | UTP14A | UTP14C | UTP15 | UTP18