Target Name: UROD
NCBI ID: G7389
Review Report on UROD Target / Biomarker Content of Review Report on UROD Target / Biomarker
UROD
Other Name(s): UROD variant 1 | OTTHUMP00000010503 | uroporphyrinogen decarboxylase | UPD | Uroporphyrinogen decarboxylase, transcript variant 1 | URO-D | DCUP_HUMAN | uroporphyrinogen III decarboxylase | Uroporphyrinogen III decarboxylase | PCT | Uroporphyrinogen decarboxylase

UROD: A Versatile Protein Involved in Energy Metabolism and More

UROD (Unregulated RecEAT-Oxidase Domain) is a protein that is expressed in various tissues and organs, including the brain, heart, liver, and kidneys. It is a member of the RecEAT gene family, which is known for its role in the regulation of energy metabolism. UROD is characterized by a unique domain that consists of 24 amino acid residues, known as the RecEAT-Oxidase domain.

The RecEAT-Oxidase domain is a conserved region that is present in a variety of organisms, including bacteria, archaea, and eukaryotes. It is involved in the catalytic activity of the enzyme RecEAT, which is a critical regulator of cellular energy metabolism. The RecEAT-Oxidase domain is responsible for the catalytic activity of the enzyme, as well as its stability and substrate specificity.

UROD is a versatile protein that can be modified to serve as a drug target or biomarker. One of the main advantages of UROD is its high degree of flexibility. Its RecEAT-Oxidase domain can be modified to have different catalytic activities, which can be used to target specific molecules in the body. Additionally, UROD can be modified to have different stability and solubility characteristics, which can be used to improve its stability and effectiveness in the body.

UROD has been shown to be involved in a variety of cellular processes, including energy metabolism, metabolism, and stress response. It has been shown to play a role in the regulation of cellular processes that are important for the health and survival of the body, such as the regulation of cell death, the regulation of inflammation, and the regulation of metabolism.

UROD is also a potential biomarker for a variety of diseases. Its recessive allele has been shown to be associated with a number of diseases, including cancer, neurodegenerative diseases, and cardiovascular diseases. Additionally, UROD has been shown to be involved in the regulation of cellular processes that are important for the development and progression of these diseases, which may be potential targets for diagnostic and therapeutic interventions.

UROD is a unique protein that is expressed in various tissues and organs, and its RecEAT-Oxidase domain makes it a promising drug target or biomarker. Further research is needed to fully understand its role in the regulation of cellular processes and its potential as a drug target or biomarker.

Protein Name: Uroporphyrinogen Decarboxylase

Functions: Catalyzes the sequential decarboxylation of the four acetate side chains of uroporphyrinogen to form coproporphyrinogen and participates in the fifth step in the heme biosynthetic pathway (PubMed:14633982, PubMed:11069625, PubMed:21668429, PubMed:11719352). Isomer I or isomer III of uroporphyrinogen may serve as substrate, but only coproporphyrinogen III can ultimately be converted to heme (PubMed:14633982, PubMed:11069625, PubMed:21668429, PubMed:11719352). In vitro also decarboxylates pentacarboxylate porphyrinogen I (PubMed:12071824)

The "UROD Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about UROD comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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UROS | USB1 | USE1 | USF1 | USF2 | USF3 | USH1C | USH1G | USH2A | USHBP1 | USO1 | USP1 | USP1-UAF1 complex | USP10 | USP11 | USP12 | USP12-AS1 | USP12-DT | USP13 | USP14 | USP15 | USP16 | USP17L1 | USP17L10 | USP17L11 | USP17L12 | USP17L13 | USP17L14P | USP17L15 | USP17L17 | USP17L18 | USP17L2 | USP17L20 | USP17L21 | USP17L24 | USP17L25 | USP17L26 | USP17L27 | USP17L29 | USP17L3 | USP17L5 | USP17L6P | USP17L7 | USP17L8 | USP17L9P | USP18 | USP19 | USP2 | USP2-AS1 | USP20 | USP21 | USP22 | USP24 | USP25 | USP26 | USP27X | USP27X-DT | USP28 | USP29 | USP3 | USP3-AS1 | USP30 | USP30-AS1 | USP31 | USP32 | USP32P1 | USP32P2 | USP32P3 | USP33 | USP34 | USP35 | USP36 | USP37 | USP38 | USP39 | USP4 | USP40 | USP41 | USP42 | USP43 | USP44 | USP45 | USP46 | USP46-DT | USP47 | USP48 | USP49 | USP5 | USP50 | USP51 | USP53 | USP54 | USP6 | USP6NL | USP6NL intronic transcript 1 (non-protein coding), transcript variant 1 | USP7 | USP8 | USP8P1 | USP9X | USP9Y