Target Name: USP17L26
NCBI ID: G728379
Review Report on USP17L26 Target / Biomarker Content of Review Report on USP17L26 Target / Biomarker
USP17L26
Other Name(s): LOC728373 | LOC728400 | LOC728379 | LOC728419 | similar to deubiquitinating enzyme 3 | Deubiquitinating enzyme 17 | LOC728393 | Ubiquitin carboxyl-terminal hydrolase 17-like protein 24 | Ubiquitin specific peptidase 17 like family member 26 | Ubiquitin-specific-processing protease 17 | LOC728369 | ubiquitin specific peptidase 17 like family member 26 | Ubiquitin thioesterase 17 | LOC728405 | U17LO_HUMAN

USP17L26: A Potential Drug Target and Biomarker

USP17L26 is a protein that is expressed in various tissues of the body, including the brain, heart, and liver. Its unique structure and subcellular localization have led to its potential as a drug target or biomarker. This article will discuss the characterization of USP17L26, its potential drug targets, and its potential as a biomarker for various diseases.

Characterization of USP17L26

USP17L26 is a 26kDa protein that is expressed in various tissues of the body. It is predominantly expressed in the brain, with lower levels found in the heart and liver. USP17L26 is a member of the USP family, which includes a variety of transmembrane proteins involved in various cellular processes. The USP17 family has been implicated in a wide range of physiological processes, including cell signaling, migration, and invasion.

Potential Drug Targets

USP17L26 has several potential drug targets due to its unique structure and subcellular localization. One of the most promising targets is the protein p120GAP, which is a known co-factor of the USP17 family. p120GAP is a transmembrane protein that is involved in various cellular processes, including cell signaling, DNA replication, and cell survival. p120GAP has been implicated in a wide range of diseases, including cancer, neurodegenerative diseases, and mood disorders.

Another potential drug target for USP17L26 is the protein heat shock protein (Hsp70), which is involved in protein folding and stability. Hsp70 is a cytoplasmic protein that is expressed in various tissues of the body, including the brain. Hsp70 has been implicated in a wide range of diseases, including neurodegenerative diseases, cancer, and climate change.

Potential Biomarkers

USP17L26 may also be a potential biomarker for various diseases. Its unique expression pattern in various tissues of the body makes it a potential diagnostic biomarker for a wide range of diseases. For example, USP17L26 has been shown to be expressed in various tissues of the brain, including the prefrontal cortex, basal ganglia, and hippocampus. This suggests that it may be a useful biomarker for neurological diseases, such as Alzheimer's disease, Parkinson's disease, and Huntington's disease.

USP17L26 has also been shown to be expressed in various tissues of the heart, including the myocardium and the pericardium. This suggests that it may be a useful biomarker for cardiovascular diseases, such as heart failure, hypertension, and ischemia.

In addition to its potential as a biomarker, USP17L26 may also be a useful drug target for various diseases. Its unique structure and subcellular localization make it a potential target for small molecules, antibodies, or other therapeutic agents. Further studies are needed to determine the efficacy and safety of USP17L26 as a drug.

Conclusion

In conclusion, USP17L26 is a protein that has unique structure and subcellular localization, making it a potential drug target or biomarker. Its potential drug targets include p120GAP and Hsp70, and its potential as a biomarker include the diagnosis of various neurological and cardiovascular diseases. Further studies are needed to determine its efficacy and safety as a drug.

Protein Name: Ubiquitin Specific Peptidase 17 Like Family Member 26

Functions: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes that may include cell proliferation, progression through the cell cycle, apoptosis, cell migration, and the cellular response to viral infection

The "USP17L26 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about USP17L26 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

USP17L27 | USP17L29 | USP17L3 | USP17L5 | USP17L6P | USP17L7 | USP17L8 | USP17L9P | USP18 | USP19 | USP2 | USP2-AS1 | USP20 | USP21 | USP22 | USP24 | USP25 | USP26 | USP27X | USP27X-DT | USP28 | USP29 | USP3 | USP3-AS1 | USP30 | USP30-AS1 | USP31 | USP32 | USP32P1 | USP32P2 | USP32P3 | USP33 | USP34 | USP35 | USP36 | USP37 | USP38 | USP39 | USP4 | USP40 | USP41 | USP42 | USP43 | USP44 | USP45 | USP46 | USP46-DT | USP47 | USP48 | USP49 | USP5 | USP50 | USP51 | USP53 | USP54 | USP6 | USP6NL | USP6NL intronic transcript 1 (non-protein coding), transcript variant 1 | USP7 | USP8 | USP8P1 | USP9X | USP9Y | USPL1 | UST | UTF1 | UTP11 | UTP14A | UTP14C | UTP15 | UTP18 | UTP20 | UTP23 | UTP25 | UTP3 | UTP4 | UTP6 | UTRN | UTS2 | UTS2B | UTS2R | UTY | UVRAG | UVSSA | UXS1 | UXT | UXT-AS1 | VAC14 | Vacuolar H+ ATPase | VAMP1 | VAMP2 | VAMP3 | VAMP4 | VAMP5 | VAMP7 | VAMP8 | VANGL1 | VANGL2 | VAPA | VAPB