Understanding The H4C12 Protein: A Key Regulator of The Histamine System

Target Name: H4C12

NCBI ID: G8362

H4C12

Other Name(s): HIST4H4J | HIST4H4C | H4C14 | H4F2iii | H4 clustered histone 12 | HIST4H4D | H4C8 | HIST4H4B | H4C11 | H4C9 | HIST4H4I | HIST4H4 | H4C5 | HIST2H4A | HIST4H4A | HIST2H4B | H4C6 | H4C15 | HIST4H4L | H4C3 | H4C1 | DJ160A22.1 | HIST4H4H | H4FD | H4C4 | H4/d | H4C13 | HIST1H4K | H4C2 | HIST4H4F | HIST4H4E | H4-16

Understanding The H4C12 Protein: A Key Regulator of The Histamine System

H4C12, also known as HIST4H4J, is a protein that is expressed in various tissues of the human body. It is a key player in the histamine system, which is responsible for regulating allergic responses and inflammation. The H4C12 protein has been identified as a potential drug target and biomarker for several diseases, including allergies, asthma, and autoimmune disorders.

The histamine system is a complex system that involves the release and regulation of histamines, which are derived from the body's histamine-producing cells. Histamines play a crucial role in triggering allergic reactions and causing symptoms such as itching, swelling, and inflammation. The H4C12 protein is a key regulator of the histamine system, and it has been shown to play a role in the regulation of allergic responses and inflammation.

One of the main functions of the H4C12 protein is its role in regulating the release of histamines from immune cells. When the body is exposed to an allergen, such as pollen, dust mites, etc., the H4C12 protein is activated and helps to regulate the release of histamines from immune cells. This release of histamines can cause symptoms such as itching, swelling, and inflammation.

In addition to its role in regulating the release of histamines, the H4C12 protein has also been shown to play a key role in the regulation of allergic responses. Allergic reactions are caused by an immune system that is overly sensitive to a particular allergen. protein helps to regulate the release of histamines from immune cells, which can contribute to the development of an allergic reaction.

The H4C12 protein has also been shown to be involved in the regulation of inflammation. When the body is exposed to an allergen, the H4C12 protein is activated and helps to regulate the release of histamines from immune cells. This release of histamines can cause inflammation throughout the body, leading to symptoms such as itching, swelling, and redness.

The potential drug target and biomarker status of the H4C12 protein makes it an attractive target for researchers and pharmaceutical companies. Currently, there are several drugs that are being developed to target the H4C12 protein and treat various diseases, including allergies, asthma, and autoimmune disorders. . These drugs work by inhibiting the activity of the H4C12 protein, which can help to reduce the release of histamines and alleviate symptoms.

In conclusion, the H4C12 protein is a key player in the histamine system and has been shown to play a role in the regulation of allergic responses and inflammation. Its potential as a drug target and biomarker makes it an attractive target for researchers and pharmaceutical companies. Further research is needed to fully understand the role of the H4C12 protein in the regulation of allergic responses and inflammation, and to develop effective treatments for diseases that are caused by this protein.

Protein Name: H4 Clustered Histone 12

Functions: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling

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