Target Name: INA
NCBI ID: G9118
Review Report on INA Target / Biomarker Content of Review Report on INA Target / Biomarker
INA
Other Name(s): internexin neuronal intermediate filament protein alpha | Neurofilament-66 | Internexin neuronal intermediate filament protein alpha | MGC12702 | NEF5 | Neurofilament 5 (66kD) | alpha-Inx | NF66 | TXBP-1 | AINX_HUMAN | FLJ18662 | Alpha-Inx | Alpha-internexin | FLJ57501 | Neurofilament-66, tax-binding protein | OTTHUMP00000020403 | Neurofilament 5 | 66 kDa neurofilament protein | neurofilament-66, tax-binding protein | NF-66 | neurofilament 5 (66kD)

Inhibiting INAs for Therapeutic Purposes

Internexin neuronal intermediate filament protein alpha (INA) is a protein that plays a crucial role in the structure and function of neurons. It is a member of the intermediate filament family, which are a type of protein that can be found in different cell types throughout the body. INA is expressed in many different tissues, including the brain, and is involved in the formation and maintenance of the neuron's cytoskeleton.

The cytoskeleton is the structure that surrounds the cell and provides support and stability. It is made up of a network of filaments, including INA, that are arranged in a specific pattern to support the cell and help it maintain its shape. INA is one of the most well-known of these filaments, and its role in the formation and maintenance of the neuron's cytoskeleton is critical for the proper functioning of the cell.

INGs and INs

INAs are a type of protein called intermediate filament proteins (IFPs). IFPs are a family of proteins that are characterized by the presence of a carboxylic acid residue in their amino acid sequence. This residue is important for the stability and functions of the protein, as it allows the protein to interact with other molecules in the cell.

INAs are involved in the formation and maintenance of the neuron's cytoskeleton, which is the structure that surrounds the cell and provides support and stability. The cytoskeleton is made up of a network of filaments, including INA, that are arranged in a specific pattern to support the cell and help it maintain its shape.

The INA protein is a type of IFP that is characterized by the presence of a carboxylic acid residue in its amino acid sequence. This residue is important for the stability and functions of the protein, as it allows the protein to interact with other molecules in the cell.

The INA protein is a key player in the formation and maintenance of the neuron's cytoskeleton. It is one of the most well-known of the intermediate filament proteins, and its role in this system is critical for the proper functioning of the cell.

Drugs that target INA

In recent years, researchers have become interested in the use of drugs that target INAs as a potential treatment for a variety of neurological and psychiatric disorders. This is because INAs are involved in the formation and maintenance of the neuron's cytoskeleton, and changes in the cytoskeleton have been linked to the development of these disorders.

One class of drugs that have been shown to target INAs is called taxanes. Taxanes are a type of drug that is used to treat various cancers, and they work by inhibiting the activity of tubulin, a protein that is involved in the formation and maintenance of the neuron's cytoskeleton. INAs are also involved in the formation and maintenance of the neuron's cytoskeleton, and changes in the cytoskeleton have been linked to the development of certain cancers.

Another class of drugs that have been shown to target INAs is called vasodilators. Vasodilators are a type of drug that is used to treat various cardiovascular and psychiatric disorders, and they work by relaxing the blood vessels or increasing the flow of blood to the brain. INAs are also involved in the formation and maintenance of the neuron's cytoskeleton, and changes in the cytoskeleton have been linked to the development of certain cardiovascular and psychiatric disorders.

Targeting INAs

Targeting INAs is a promising approach to treating a variety of neurological and psychiatric disorders. Because INAs are involved in the formation and maintenance of the

Protein Name: Internexin Neuronal Intermediate Filament Protein Alpha

Functions: Class-IV neuronal intermediate filament that is able to self-assemble. It is involved in the morphogenesis of neurons. It may form an independent structural network without the involvement of other neurofilaments or it may cooperate with NEFL to form the filamentous backbone to which NEFM and NEFH attach to form the cross-bridges. May also cooperate with the neuronal intermediate filament protein PRPH to form filamentous networks (By similarity)

The "INA Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about INA comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

INAFM1 | INAFM2 | INAVA | INCA1 | INCENP | INE1 | INE2 | INF2 | ING1 | ING2 | ING2-DT | ING3 | ING4 | ING5 | INGX | INHA | INHBA | INHBA-AS1 | INHBB | INHBC | INHBE | INHCAP | Inhibitor of Apoptosis Proteins (IAPs) | Inhibitory kappaB Kinase (IKK) | INIP | INKA1 | INKA2 | INKA2-AS1 | INMT | INMT-MINDY4 | Innate Repair Receptor (IRR) | INO80 | INO80 complex | INO80B | INO80B-WBP1 | INO80C | INO80D | INO80E | Inositol 1,4,5-Trisphosphate Receptor (InsP3R) | Inositol hexakisphosphate kinase | Inositol Monophosphatase | INPP1 | INPP4A | INPP4B | INPP5A | INPP5B | INPP5D | INPP5E | INPP5F | INPP5J | INPP5K | INPPL1 | INS | INS-IGF2 | INSC | INSIG1 | INSIG2 | INSL3 | INSL4 | INSL5 | INSL6 | INSM1 | INSM2 | INSR | INSRR | Insulin-like growth factor | Insulin-like growth factor 2 mRNA binding protein | Insulin-like growth factor 2 mRNA-binding protein 1 (isoform 2) | Insulin-like growth factor-binding protein | INSYN1 | INSYN2A | INSYN2B | Integrator complex | Integrin alpha1beta1 (VLA-1) receptor | Integrin alpha2beta1 (VLA-2) receptor | Integrin alpha2beta3 Receptor | Integrin alpha3beta1 receptor | Integrin alpha4beta1 (VLA-4) receptor | Integrin alpha4beta7 (LPAM-1) receptor | Integrin alpha5beta1 (VLA-5) receptor | Integrin alpha5beta3 receptor | Integrin alpha6beta1 Receptor | Integrin alpha6beta4 receptor | Integrin alpha7beta1 Receptor | Integrin alpha9beta1 receptor | Integrin alphaEbeta7 receptor | Integrin alphaLbeta2 (LFA-1) receptor | Integrin alphaMbeta2 (MAC-1) Receptor | Integrin alphavbeta1 | Integrin alphavbeta3 (vitronectin) receptor | Integrin alphavbeta5 receptor | Integrin alphavbeta6 receptor | Integrin alphavbeta8 Receptor | Integrin Receptor | Integrin-linked kinase | Interferon | Interferon-alpha (IFN-alpha) | Interferon-gamma Receptor | Interleukin 17 | Interleukin 21 receptor complex