CELSR1: A Transmembrane Protein Involved in Cell Adhesion and Cell Cycle Regulation

Target Name: CELSR1

NCBI ID: G9620

CELSR1

CELSR1: A Transmembrane Protein Involved in Cell Adhesion and Cell Cycle Regulation

CELSR1 (Protocadherin flamingo 2) is a protein that is expressed in many different tissues throughout the body. It is a member of the protocadherin gene family, which is known for its role in cell-cell adhesion. CELSR1 is primarily expressed in the liver, but it is also found in other tissues such as the heart, pancreas, and placenta.

One of the unique features of CELSR1 is its structure. It is a transmembrane protein, which means that it spans the cell membrane and is associated with the cytoskeleton. It is made up of four extracellular domains (ECD) and a single intracellular domain (ICD). The ECDs are responsible for the protein's structure and function, while the ICD is responsible for its stability and localization to the cell membrane.

CELSR1 is involved in many different processes in the body, but one of its most well-known functions is in the regulation of cell growth and differentiation. It is a negative regulator of the Wnt signaling pathway, which is a critical pathway that regulates cell growth and development.

Wnt signaling is a protein that is involved in the development and maintenance of tissues throughout the body. It is made up of four transmembrane proteins (TMs) and a protein that is secreted into the cytoplasm (SP). The TMs are responsible for transmitting signals from the embryo to the tissue, while the SP is responsible for processing and responding to those signals.

CELSR1 is one of the proteins that is involved in the regulation of the Wnt signaling pathway. It is a negative regulator of the pathway, which means that it works to inhibit the signals that are produced by the TMs. This is important because if the signals from the TMs were to be too strong, they could cause problems with cell growth and development.

CELSR1 is also involved in the regulation of cell adhesion. It is a critical protein for the development and maintenance of tissues that are in contact with the body's surface, such as the skin and the lining of the various body cavities. It helps to ensure that these tissues remain tight and organized, which is important for their proper function.

In addition to its role in cell growth and differentiation, CELSR1 is also involved in the regulation of many other processes in the body. For example, it is a negative regulator of the Notch signaling pathway, which is involved in the development and maintenance of tissues throughout the body. It is also involved in the regulation of the cell cycle, which is the process by which cells grow and divide.

CELSR1 is a protein that is expressed in many different tissues throughout the body. It is a member of the protocadherin gene family and is involved in many different processes in the body, including the regulation of cell growth and differentiation, cell adhesion, and the cell cycle. Its unique structure and its involvement in the Wnt and Notch signaling pathways make it an attractive potential drug target or biomarker. Further studies are needed to fully understand the role of CELSR1 in the regulation of cell biology and to determine its potential as a drug.

Protein Name: Cadherin EGF LAG Seven-pass G-type Receptor 1

Functions: Receptor that may have an important role in cell/cell signaling during nervous system formation

The "CELSR1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CELSR1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets