ACAP1: A GPCR Receptor with Multiple Functions and Potential Drug Targets

Target Name: ACAP1

NCBI ID: G9744

ACAP1

ACAP1: A GPCR Receptor with Multiple Functions and Potential Drug Targets

ACAP1 (Centaurin, beta 1) is a protein that is expressed in various tissues throughout the body, including the brain, heart, and kidneys. It is a member of the G-protein-coupled receptor (GPCR) family, which is a large superfamily of transmembrane proteins that play a critical role in cellular signaling.

ACAP1 is known for its role in the regulation of ion channels, which are critical for the flow of electrical signals through cells. In particular, ACAP1 is involved in the regulation of potassium channels, which are responsible for maintaining the resting membrane potential of nerves and muscle cells.

Studies have shown that ACAP1 is involved in a wide range of physiological processes in the body, including muscle contractions, blood pressure, and inflammation. It has also been shown to play a key role in the development and progression of various diseases, including heart failure , hypertension, and neurodegenerative disorders.

Due to its involvement in so many important physiological processes, ACAP1 has naturally become a potential drug target (or biomarker). In recent years, many studies have been devoted to exploring the potential of ACAP1 as a drug target or biomarker.

Among them, the possibility of ACAP1 as a drug target mainly stems from its characteristics as a GPCR receptor. Since the molecular mechanism of the GPCR family is very complex, studying the pharmacological properties of ACAP1 requires a series of experimental techniques. For example, the function of ACAP1 can be detected through methods such as potassium ion gradients inside and outside cells, fluorescence microscopy, and electrochemical experiments.

In addition, ACAP1 has also been proven to have multiple biomarker properties. For example, it can be used as a measure of blood pressure and heart rate, as well as a measure of neuronal activity. These properties make ACAP1 a very useful biomarker that can help doctors evaluate patients' disease status and treatment effects.

ACAP1 is also closely related to the occurrence and development of various diseases. For example, studies have shown that increased levels of ACAP1 can increase the risk of nerve cell death, thereby exacerbating the development of neurodegenerative diseases. In addition, ACAP1 is also closely related to various chronic diseases such as hypertension and heart disease. Therefore, the study of ACAP1 is of great significance for understanding the pathogenesis and treatment of these diseases.

Although ACAP1 is a very promising drug target or biomarker, in-depth research on it still needs further development.

Protein Name: ArfGAP With Coiled-coil, Ankyrin Repeat And PH Domains 1

Functions: GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6) required for clathrin-dependent export of proteins from recycling endosomes to trans-Golgi network and cell surface. Required for regulated export of ITGB1 from recycling endosomes to the cell surface and ITGB1-dependent cell migration

The "ACAP1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ACAP1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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