Target Name: URB2
NCBI ID: G9816
Review Report on URB2 Target / Biomarker Content of Review Report on URB2 Target / Biomarker
URB2
Other Name(s): KIAA0133 | nucleolar preribosomal-associated protein 1 | URB2 ribosome biogenesis homolog, transcript variant 2 | nucleolar preribosomal-associated protein 2 | NPA2 | Unhealthy ribosome biogenesis protein 2 homolog | URB2 ribosome biogenesis homolog | URB2 ribosome biogenesis 2 homolog | unhealthy ribosome biogenesis protein 2 homolog | URB2 variant 2 | NET10 | URB2_HUMAN

URB2: A Key Molecule in DNA Replication and Repair

URB2 (uracil nucleoside diphosphate) is a molecule that plays a crucial role in the regulation of DNA replication and repair in the human body. It is a key component of the DNA replication complex, which is responsible for copying the genetic information from the DNA template to the newly synthesized RNA molecule. URB2 is a small protein that functions as a scaffold to hold the replication complex together and ensure that the DNA double helix is 鈥嬧?媟eplicated accurately.

URB2 is also involved in the regulation of cell growth and division. It has been shown to play a role in the G1 phase of cell growth, where the cell prepares for cell division by producing a sufficient amount of DNA. During the S phase, URB2 helps to ensure that the replicated DNA is stable and protected from degradation, which allows the cell to prepare for cell division.

In addition to its role in cell growth and division, URB2 is also a potential drug target. Its involvement in DNA replication and repair makes it a promising target for small molecule inhibitors, which could be used to treat a variety of diseases. For example, URB2 has been shown to be involved in the development of certain types of cancer, so inhibitors of URB2 have been shown to be effective in treating these cancers.

URB2 is also a potential biomarker for certain types of cancer. Its involvement in DNA replication and repair makes it an attractive target for diagnostic tests that are used to detect cancer. For example, URB2 has been shown to be expressed in the blood and lymphatic systems of many types of cancer, including breast, ovarian, and prostate cancers. Therefore, measuring the level of URB2 in these tissues could be a useful diagnostic tool for cancer detection.

URB2 is also involved in the regulation of DNA repair, which is a critical process that helps the body to repair damaged DNA. When DNA is damaged, the cell's repair machinery is activated to repair the damage. URB2 plays a role in this process by helping to ensure that the repair machinery is properly assembled and that the damaged DNA is properly repaired.

In addition to its role in DNA repair, URB2 is also involved in the regulation of DNA replication. It is a key component of the DNA replication complex, which is responsible for copying the genetic information from the DNA template to the newly synthesized RNA molecule. URB2 helps to ensure that the DNA double helix is 鈥嬧?媟eplicated accurately, which is critical for the production of accurate copies of the genetic information.

URB2 is a small protein that plays a crucial role in the regulation of DNA replication and repair in the human body. Its involvement in these processes makes it an attractive target for small molecule inhibitors, which could be used to treat a variety of diseases. In addition, URB2 is also a potential biomarker for certain types of cancer and can be used as a diagnostic tool for cancer detection. Further research is needed to fully understand the role of URB2 in the regulation of DNA replication and repair, and to develop effective treatments for the diseases that are associated with these processes.

Protein Name: URB2 Ribosome Biogenesis Homolog

Functions: Essential for hematopietic stem cell development through the regulation of p53/TP53 pathway

The "URB2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about URB2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

Urea transporter | URGCP | URGCP-MRPS24 | URI1 | Uridine phosphorylase | URM1 | UROC1 | UROD | UROS | USB1 | USE1 | USF1 | USF2 | USF3 | USH1C | USH1G | USH2A | USHBP1 | USO1 | USP1 | USP1-UAF1 complex | USP10 | USP11 | USP12 | USP12-AS1 | USP12-DT | USP13 | USP14 | USP15 | USP16 | USP17L1 | USP17L10 | USP17L11 | USP17L12 | USP17L13 | USP17L14P | USP17L15 | USP17L17 | USP17L18 | USP17L2 | USP17L20 | USP17L21 | USP17L24 | USP17L25 | USP17L26 | USP17L27 | USP17L29 | USP17L3 | USP17L5 | USP17L6P | USP17L7 | USP17L8 | USP17L9P | USP18 | USP19 | USP2 | USP2-AS1 | USP20 | USP21 | USP22 | USP24 | USP25 | USP26 | USP27X | USP27X-DT | USP28 | USP29 | USP3 | USP3-AS1 | USP30 | USP30-AS1 | USP31 | USP32 | USP32P1 | USP32P2 | USP32P3 | USP33 | USP34 | USP35 | USP36 | USP37 | USP38 | USP39 | USP4 | USP40 | USP41 | USP42 | USP43 | USP44 | USP45 | USP46 | USP46-DT | USP47 | USP48 | USP49 | USP5 | USP50 | USP51 | USP53 | USP54