ATP6AP2: A Potential Drug Target and Biomarker (G10159)

Target Name: ATP6AP2

NCBI ID: G10159

ATP6AP2

ATP6AP2: A Potential Drug Target and Biomarker

ATP (adenosine triphosphate) is a crucial molecule in the cell's energy metabolism. It is involved in the transfer of energy from the cell's energy reserves to various cellular processes, including muscle contractions, neural transmission, and chromatin regulation. The protein ATP6AP2 has been identified as a potential drug target and biomarker in various diseases, including cancer, neurodegenerative diseases, and metabolic disorders.

ATP6AP2 is a key regulator of the cell's energy metabolism and plays a crucial role in the production of adenosine, which is a potent antioxidant that helps protect the cell from damage caused by reactive oxygen species. In addition to its role in energy metabolism, ATP6AP2 is also involved in the regulation of cell signaling pathways, including the production of signaling molecules such as nitric oxide, which plays a critical role in cardiovascular health.

The identification of ATP6AP2 as a potential drug target and biomarker has been based on several studies that have demonstrated its involvement in various diseases. For example, studies have shown that ATP6AP2 is involved in the regulation of cancer cell growth and progression, and that its levels are often elevated in cancer cells compared to healthy cells. In addition, research has also shown that ATP6AP2 is involved in the development and progression of neurodegenerative diseases, including Alzheimer's and Parkinson's diseases.

In addition to its potential as a drug target, ATP6AP2 has also been identified as a potential biomarker for several diseases. For example, studies have shown that ATP6AP2 levels are often elevated in individuals with Alzheimer's disease, and that levels are also associated with poor clinical outcomes in these individuals. Similarly, research has also shown that ATP6AP2 is involved in the regulation of glucose metabolism, and that its levels are often elevated in individuals with diabetes.

The identification of ATP6AP2 as a potential drug target and biomarker has important implications for the development of new treatments for a variety of diseases. By targeting ATP6AP2, researchers may be able to develop new drugs that can treat diseases such as cancer, neurodegenerative diseases, and metabolic disorders. Additionally, the development of ATP6AP2 as a biomarker could help diagnose and monitor these diseases more effectively.

In conclusion, ATP6AP2 is a protein that plays a crucial role in the cell's energy metabolism and has been identified as a potential drug target and biomarker in a variety of diseases. Further research is needed to fully understand its role in these diseases and to develop new treatments based on its properties.

Protein Name: ATPase H+ Transporting Accessory Protein 2

Functions: Multifunctional protein which functions as a renin, prorenin cellular receptor and is involved in the assembly of the lysosomal proton-transporting V-type ATPase (V-ATPase) and the acidification of the endo-lysosomal system (PubMed:12045255, PubMed:29127204, PubMed:30374053, PubMed:32276428). May mediate renin-dependent cellular responses by activating ERK1 and ERK2 (PubMed:12045255). By increasing the catalytic efficiency of renin in AGT/angiotensinogen conversion to angiotensin I, may also play a role in the renin-angiotensin system (RAS) (PubMed:12045255). Through its function in V-type ATPase (v-ATPase) assembly and acidification of the lysosome it regulates protein degradation and may control different signaling pathways important for proper brain development, synapse morphology and synaptic transmission (By similarity)

The "ATP6AP2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ATP6AP2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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