GPR176: A Potential Drug Target for Pain Disorders (G11245)
GPR176: A Potential Drug Target for Pain Disorders
GPR176 (also known as Gm1012) is a protein that is expressed in the brain and is known for its role in the regulation of pain signaling. It is a G protein-coupled receptor (GPCR), which means that it is a receptor that is targeted by a protein called G protein. The GPCR system is a complex cell signaling system that is involved in a wide range of physiological processes, including pain signaling.
GPR176 is a transmembrane protein that is located in the endoplasmic reticulum (ER) and is involved in the regulation of pain signaling. It is a potent modulator of pain signaling, with studies showing that it can inhibit the activity of pain-related GPCRs and modulate the activity of non-pain-related GPCRs. This suggests that GPR176 may be a useful drug target for the treatment of pain disorders.
GPR176 is also known as Gm1012 because it is a member of the Gm1012 family of GPCRs. The Gm1012 family is a subset of the GPCR family that includes GPR82, GPR83, GPR85, GPR86, and GPR87. These proteins are involved in a wide range of physiological processes, including pain signaling, neurodegenerative diseases, and sensory processing.
GPR176 is expressed in the brain and is involved in the regulation of pain signaling in this Organ. It is a potent modulator of pain signaling, with studies showing that it can inhibit the activity of pain-related GPCRs and modulate the activity of non-pain-related GPCRs. This suggests that GPR176 may be a useful drug target for the treatment of pain disorders.
GPR176 is a transmembrane protein that is located in the endoplasmic reticulum (ER) and is involved in the regulation of pain signaling. It is a potent modulator of pain signaling, with studies showing that it can inhibit the activity of pain-related GPCRs and modulate the activity of non-pain-related GPCRs. This suggests that GPR176 may be a useful drug target for the treatment of pain disorders.
Protein Name: G Protein-coupled Receptor 176
Functions: Orphan receptor involved in normal circadian rhythm behavior. Acts through the G-protein subclass G(z)-alpha and has an agonist-independent basal activity to repress cAMP production
The "GPR176 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about GPR176 comprehensively, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
More Common Targets
GPR179 | GPR18 | GPR180 | GPR182 | GPR183 | GPR19 | GPR199P | GPR20 | GPR21 | GPR22 | GPR25 | GPR26 | GPR27 | GPR3 | GPR31 | GPR32 | GPR33 | GPR34 | GPR35 | GPR37 | GPR37L1 | GPR39 | GPR4 | GPR42 | GPR45 | GPR50 | GPR52 | GPR55 | GPR6 | GPR61 | GPR62 | GPR63 | GPR65 | GPR68 | GPR75 | GPR75-ASB3 | GPR78 | GPR79 | GPR82 | GPR83 | GPR84 | GPR84-AS1 | GPR85 | GPR87 | GPR88 | GPR89A | GPR89B | GPRACR | GPRASP1 | GPRASP2 | GPRASP3 | GPRC5A | GPRC5B | GPRC5C | GPRC5D | GPRC5D-AS1 | GPRC6A | GPRIN1 | GPRIN2 | GPRIN3 | GPS, PLAT and transmembrane domain-containing protein | GPS1 | GPS2 | GPS2P1 | GPSM1 | GPSM2 | GPSM3 | GPT | GPT2 | GPX1 | GPX1P1 | GPX2 | GPX3 | GPX4 | GPX5 | GPX6 | GPX7 | GPX8 | GRAMD1A | GRAMD1B | GRAMD1C | GRAMD2A | GRAMD2B | GRAMD4 | GRAMD4P2 | GRAMD4P5 | GRAMD4P7 | Granzyme | GRAP | GRAP2 | GRAPL | GRAPL-AS1 | GRASLND | GRB10 | GRB14 | GRB2 | GRB7 | GREB1 | GREB1L | GREM1
