Target Name: WASF2
NCBI ID: G10163
Review Report on WASF2 Target / Biomarker Content of Review Report on WASF2 Target / Biomarker
WASF2
Other Name(s): wiskott-Aldrich syndrome protein family member 2 | SCAR2 | WASF2 variant 1 | WASF2_HUMAN | Verprolin homology domain-containing protein 2 | dJ393P12.2 | WASP family Verprolin-homologous protein 2 | IMD2 | Protein WAVE-2 | putative Wiskott-Aldrich syndrome protein family member 4 | WAVE2 | WAS protein family member 2 | suppressor of cyclic-AMP receptor (WASP-family) | WASP family member 2 | verprolin homology domain-containing protein 2 | Wiskott-Aldrich syndrome protein family member 2 (isoform 1) | WASF4 | Suppressor of cyclic-AMP receptor (WASP-family) | protein WAVE-2 | WASP family protein member 4 | WASP family protein member 2 | Actin-binding protein WASF2

WASF2: A Drug Target / Disease Biomarker

WASF2, short for Wiskott-Ashley syndrome family 2, is a rare autosomal recessive disease that is characterized by splenomegaly, anemia, and anemia-related symptoms. The disease is caused by a deficiency of the protein WASF2, which is a key regulator of hematopoietic stem cells.

WASF2 is a transmembrane protein that is expressed in a variety of tissues, including the bone marrow, where it plays a crucial role in the development and maturation of hematopoietic stem cells. In addition to its role in hematopoietic stem cells, WASF2 is also involved in the regulation of inflammation and immune response.

The WASF2 gene has been identified as a potential drug target for the treatment of various diseases, including cancer, autoimmune disorders, and genetic disorders. The discovery of WASF2 as a drug target has led to a greater understanding of the underlying mechanisms of the disease and has the potential to lead to new treatments.

One of the main mechanisms by which WASF2 regulates hematopoietic stem cells is through the regulation of the stem cell proliferation cycle. WASF2 has been shown to play a role in the regulation of G1 checkout, a critical checkpoint in the cell cycle that ensures that cells have enough nutrients and oxygen to divide and grow.

WASF2 has also been shown to regulate the differentiation of hematopoietic stem cells into functional blood cells. Studies have shown that WASF2 plays a critical role in the development of mature red blood cells, which are responsible for carrying oxygen from the lungs to the rest of the body.

In addition to its role in hematopoietic stem cells, WASF2 is also involved in the regulation of inflammation and immune response. Studies have shown that WASF2 plays a role in the regulation of T cell development and that it is involved in the regulation of inflammation.

WASF2 has also been shown to be involved in the regulation of autoimmune disorders. Studies have shown that WASF2 plays a role in the regulation of the development and function of immune cells, which are responsible for recognizing and responding to foreign substances in the body.

In conclusion, WASF2 is a protein that plays a crucial role in the regulation of hematopoietic stem cells and has the potential to be a drug target for the treatment of various diseases, including cancer, autoimmune disorders, and genetic disorders. Further research is needed to fully understand the role of WASF2 in the regulation of hematopoietic stem cells and to develop new treatments for these diseases.

Protein Name: WASP Family Member 2

Functions: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex

The "WASF2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about WASF2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

WASF3 | WASF4P | WASF5P | WASH complex | WASH2P | WASH3P | WASH4P | WASH5P | WASH6P | WASH7P | WASH8P | WASHC1 | WASHC2A | WASHC2C | WASHC3 | WASHC4 | WASHC5 | WASIR1 | WASL | WAVE1 complex | WBP1 | WBP11 | WBP11P1 | WBP1L | WBP2 | WBP2NL | WBP4 | WDCP | WDFY1 | WDFY2 | WDFY3 | WDFY3-AS2 | WDFY4 | WDHD1 | WDPCP | WDR1 | WDR11 | WDR11-DT | WDR12 | WDR13 | WDR17 | WDR18 | WDR19 | WDR20 | WDR24 | WDR25 | WDR26 | WDR27 | WDR3 | WDR31 | WDR33 | WDR35 | WDR35-DT | WDR36 | WDR37 | WDR38 | WDR4 | WDR41 | WDR43 | WDR44 | WDR45 | WDR45B | WDR46 | WDR47 | WDR48 | WDR49 | WDR5 | WDR53 | WDR54 | WDR55 | WDR59 | WDR5B | WDR6 | WDR62 | WDR64 | WDR7 | WDR70 | WDR72 | WDR73 | WDR74 | WDR75 | WDR76 | WDR77 | WDR81 | WDR82 | WDR82P1 | WDR83 | WDR83OS | WDR86 | WDR86-AS1 | WDR87 | WDR88 | WDR89 | WDR90 | WDR91 | WDR93 | WDR97 | WDSUB1 | WDTC1 | WEE1