Target Name: WASF1
NCBI ID: G8936
Review Report on WASF1 Target / Biomarker Content of Review Report on WASF1 Target / Biomarker
WASF1
Other Name(s): WASP family protein member 1 | WASF1_HUMAN | protein WAVE-1 | WASP family member 1 | verprolin homology domain-containing protein 1 | wiskott-Aldrich syndrome protein family member 1 | Verprolin homology domain-containing protein 1 | FLJ31482 | KIAA0269 | Protein WAVE-1 | WAVE1 | WAS protein family member 1 | homology of dictyostelium scar 1 | SCAR1 | NEDALVS | OTTHUMP00000016990 | OTTHUMP00000016992 | WASF1 variant 1 | WAVE | Actin-binding protein WASF1 | Homology of dictyostelium scar 1 | Wiskott-Aldrich syndrome protein family member 1

WASF1: A Protein with Great Potential as A Drug Target

WASF1, also known as WASP-1, is a protein that belongs to the WASP family, which is a group of proteins that are involved in various cellular processes such as cell signaling, cytoskeletal organization, and inflammation. WASF1 is a 21-kDa protein that is expressed in a variety of tissues, including muscle, bone, and various organs.

WASF1 has been identified as a potential drug target and a biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Its unique structure and various functions have made it an attractive target for researchers to study and develop new treatments.

One of the key features of WASF1 is its modular structure. The protein is composed of several distinct domains, including an N-terminal transmembrane domain, a coiled-coil domain, and a C-terminal T-loop domain. The transmembrane domain is responsible for the protein's ability to interact with various signaling molecules, while the coiled-coil domain and T-loop domain are involved in the protein's stability and interactions with other proteins.

WASF1 has been shown to play a role in various cellular processes, including cell signaling, cytoskeletal organization, and inflammation. For example, WASF1 has been shown to be involved in the regulation of muscle contractions and in the development of cancer.

In addition to its role in cellular signaling, WASF1 has also been shown to be involved in the regulation of cellular processes related to inflammation. For example, studies have shown that WASF1 can modulate the activity of immune cells and influence the development of inflammatory diseases.

WASF1's modular structure and various functions have made it an attractive target for researchers to study and develop new treatments. Its potential as a drug target makes it an important area of research for the development of new treatments for a variety of diseases.

In conclusion, WASF1 is a protein that has great potential as a drug target and biomarker. Its modular structure and various functions make it an attractive target for researchers to study and develop new treatments for a variety of diseases. Further research is needed to fully understand the role of WASF1 in cellular processes and its potential as a drug target.

Protein Name: WASP Family Member 1

Functions: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation (PubMed:29961568). The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex (By similarity). As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (By similarity). Also involved in the regulation of mitochondrial dynamics (PubMed:29961568)

The "WASF1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about WASF1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

WASF2 | WASF3 | WASF4P | WASF5P | WASH complex | WASH2P | WASH3P | WASH4P | WASH5P | WASH6P | WASH7P | WASH8P | WASHC1 | WASHC2A | WASHC2C | WASHC3 | WASHC4 | WASHC5 | WASIR1 | WASL | WAVE1 complex | WBP1 | WBP11 | WBP11P1 | WBP1L | WBP2 | WBP2NL | WBP4 | WDCP | WDFY1 | WDFY2 | WDFY3 | WDFY3-AS2 | WDFY4 | WDHD1 | WDPCP | WDR1 | WDR11 | WDR11-DT | WDR12 | WDR13 | WDR17 | WDR18 | WDR19 | WDR20 | WDR24 | WDR25 | WDR26 | WDR27 | WDR3 | WDR31 | WDR33 | WDR35 | WDR35-DT | WDR36 | WDR37 | WDR38 | WDR4 | WDR41 | WDR43 | WDR44 | WDR45 | WDR45B | WDR46 | WDR47 | WDR48 | WDR49 | WDR5 | WDR53 | WDR54 | WDR55 | WDR59 | WDR5B | WDR6 | WDR62 | WDR64 | WDR7 | WDR70 | WDR72 | WDR73 | WDR74 | WDR75 | WDR76 | WDR77 | WDR81 | WDR82 | WDR82P1 | WDR83 | WDR83OS | WDR86 | WDR86-AS1 | WDR87 | WDR88 | WDR89 | WDR90 | WDR91 | WDR93 | WDR97 | WDSUB1 | WDTC1