Target Name: WAPL
NCBI ID: G23063
Review Report on WAPL Target / Biomarker Content of Review Report on WAPL Target / Biomarker
WAPL
Other Name(s): Wings apart-like protein homolog | Friend of EBNA2 protein | Wings apart-like protein (Drosophila) | Friend of EBNA2 (Epstein-Barr virus nuclear protein 2) | friend of EBNA2 protein | Human wings apart-like | WAPL variant 1 | friend of EBNA2 (Epstein-Barr virus nuclear protein 2) | FOE | KIAA0261 | WAPAL | WAPL_HUMAN | Wings apart-like protein homolog (isoform 1) | WAPL cohesin release factor | WAPL cohesin release factor, transcript variant 1

Wings Apart-like Protein Homolog: Potential Drug Target

Wings apart-like protein homolog (WAPL) is a protein that is found in various organisms, including humans. It is a member of the superfamily of proteins known as the wingspan protein family, which is characterized by the presence of a characteristic wing-like structure in the protein sequence. WAPL is involved in a variety of cellular processes, including cell signaling, DNA replication, and response to stimuli.

One of the unique features of WAPL is its ability to form clusters. These clusters, called domains, are regions of the protein that are important for its function. WAPL can form domains that range in size from a few amino acids to over 200 amino acids long. The clusters are arranged in a specific pattern, called a \"wing-like\" structure, that is thought to reflect the protein's function in cell signaling.

WAPL has been shown to play a role in a variety of cellular processes. For example, it has been shown to be involved in cell signaling, particularly in the regulation of cell growth and differentiation. In addition, WAPL has been shown to be involved in DNA replication, which is a critical process for cell growth and development.

Another important function of WAPL is its ability to respond to stimuli. For example, WAPL has been shown to play a role in the regulation of pain, particularly in the context of neuroinflammation. In addition, WAPL has been shown to play a role in the regulation of inflammation, which is important for both physical and biological health.

WAPL is also of interest as a potential drug target. Its unique wing-like structure and its involvement in a variety of cellular processes make it an attractive target for drug development. In addition, its ability to form domains of various sizes and its ability to form clusters provide a unique mechanism for drug targeting.

In conclusion, Wings apart-like protein homolog (WAPL) is a protein that is of interest as a potential drug target. Its unique wing-like structure and its involvement in a variety of cellular processes make it an attractive target for drug development. Further research is needed to fully understand its function and its potential as a drug.

Protein Name: WAPL Cohesin Release Factor

Functions: Regulator of sister chromatid cohesion in mitosis which negatively regulates cohesin association with chromatin. Involved in both sister chromatid cohesion during interphase and sister-chromatid resolution during early stages of mitosis. Couples DNA replication to sister chromatid cohesion. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair

The "WAPL Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about WAPL comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

WARS1 | WARS2 | WARS2-AS1 | WAS | WASF1 | WASF2 | WASF3 | WASF4P | WASF5P | WASH complex | WASH2P | WASH3P | WASH4P | WASH5P | WASH6P | WASH7P | WASH8P | WASHC1 | WASHC2A | WASHC2C | WASHC3 | WASHC4 | WASHC5 | WASIR1 | WASL | WAVE1 complex | WBP1 | WBP11 | WBP11P1 | WBP1L | WBP2 | WBP2NL | WBP4 | WDCP | WDFY1 | WDFY2 | WDFY3 | WDFY3-AS2 | WDFY4 | WDHD1 | WDPCP | WDR1 | WDR11 | WDR11-DT | WDR12 | WDR13 | WDR17 | WDR18 | WDR19 | WDR20 | WDR24 | WDR25 | WDR26 | WDR27 | WDR3 | WDR31 | WDR33 | WDR35 | WDR35-DT | WDR36 | WDR37 | WDR38 | WDR4 | WDR41 | WDR43 | WDR44 | WDR45 | WDR45B | WDR46 | WDR47 | WDR48 | WDR49 | WDR5 | WDR53 | WDR54 | WDR55 | WDR59 | WDR5B | WDR6 | WDR62 | WDR64 | WDR7 | WDR70 | WDR72 | WDR73 | WDR74 | WDR75 | WDR76 | WDR77 | WDR81 | WDR82 | WDR82P1 | WDR83 | WDR83OS | WDR86 | WDR86-AS1 | WDR87 | WDR88 | WDR89 | WDR90