WashC4: A Potential Drug Target for Cancer (G23325)
WashC4: A Potential Drug Target for Cancer
WashC4 (MRT43), a gene that encodes a protein involved in the development and maintenance of cancer cells, has recently been identified as a potential drug target or biomarker for the treatment of various diseases, including cancer. The discovery of WashC4 and its potential role in disease makes it an important step forward in the fight against cancer.
The protein encoded by WashC4 is a member of the microtubule-associated protein (MAP) family, which plays a critical role in the mechanical properties of cells. MAPs are involved in the regulation of cell division, differentiation, and transport of organelles within the cell. WashC4 is specifically involved in the regulation of mitotic spindle stability, which is a critical step in the cell cycle and leads to the formation of new cell plates during mitosis.
The role of WashC4 in cancer development is still being fully understood, but research has shown that high levels of WashC4 expression are associated with the development and progression of various cancers, including breast, ovarian, and colorectal cancers. Additionally, WashC4 has been shown to promote the growth and survival of cancer cells in cell culture and animal models.
Due to its involvement in the regulation of mitotic spindle stability, WashC4 has been identified as a potential drug target or biomarker for the treatment of cancer. By targeting WashC4 with small molecules or other compounds, researchers hope to inhibit its activity and reduce the growth and survival of cancer cells. This could lead to the development of new treatments for various cancers and improve the overall health and wellbeing of patients.
In addition to its potential as a drug target or biomarker, WashC4 has also been shown to be involved in the regulation of other cellular processes that are important for cancer development. For example, studies have shown that high levels of WashC4 expression are associated with the development of neurodegenerative diseases, including Alzheimer's and Parkinson's diseases. Additionally, WashC4 has been shown to be involved in the regulation of the immune response, which is important for the treatment of many types of cancer.
Overall, the discovery of WashC4 and its potential as a drug target or biomarker for cancer makes it an important finding with implications for the treatment of a wide range of diseases. Further research is needed to fully understand the role of WashC4 in disease and to develop effective treatments for the treatment of cancer and other diseases.
Protein Name: WASH Complex Subunit 4
Functions: Acts as a component of the WASH core complex that functions as a nucleation-promoting factor (NPF) at the surface of endosomes, where it recruits and activates the Arp2/3 complex to induce actin polymerization, playing a key role in the fission of tubules that serve as transport intermediates during endosome sorting
The "WASHC4 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about WASHC4 comprehensively, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
More Common Targets
WASHC5 | WASIR1 | WASL | WAVE1 complex | WBP1 | WBP11 | WBP11P1 | WBP1L | WBP2 | WBP2NL | WBP4 | WDCP | WDFY1 | WDFY2 | WDFY3 | WDFY3-AS2 | WDFY4 | WDHD1 | WDPCP | WDR1 | WDR11 | WDR11-DT | WDR12 | WDR13 | WDR17 | WDR18 | WDR19 | WDR20 | WDR24 | WDR25 | WDR26 | WDR27 | WDR3 | WDR31 | WDR33 | WDR35 | WDR35-DT | WDR36 | WDR37 | WDR38 | WDR4 | WDR41 | WDR43 | WDR44 | WDR45 | WDR45B | WDR46 | WDR47 | WDR48 | WDR49 | WDR5 | WDR53 | WDR54 | WDR55 | WDR59 | WDR5B | WDR6 | WDR62 | WDR64 | WDR7 | WDR70 | WDR72 | WDR73 | WDR74 | WDR75 | WDR76 | WDR77 | WDR81 | WDR82 | WDR82P1 | WDR83 | WDR83OS | WDR86 | WDR86-AS1 | WDR87 | WDR88 | WDR89 | WDR90 | WDR91 | WDR93 | WDR97 | WDSUB1 | WDTC1 | WEE1 | WEE2 | WEE2-AS1 | WFDC1 | WFDC10A | WFDC10B | WFDC11 | WFDC12 | WFDC13 | WFDC2 | WFDC21P | WFDC3 | WFDC5 | WFDC6 | WFDC8 | WFDC9 | WFIKKN1
