The Potential of WAC as A Cancer Drug Target and Biomarker (G51322)
The Potential of WAC as A Cancer Drug Target and Biomarker
WAC, which stands for World's Best Cancer, is a protein that is found in various forms in the human body. It is a domain-containing adapter protein with coiled-coil, which is a protein structure that plays a crucial role in various biological processes. WAC is known for its ability to interact with other proteins and molecules, which makes it an attractive drug target or biomarker in the fight against cancer.
The Importance of WAC
WAC plays a vital role in the development and progression of cancer. It is a key regulator of the cell-cell adhesion process, which helps to maintain the integrity of the immune system and keep the cell cycle in check. WAC is also involved in the regulation of cell growth and the control of apoptosis, which are processes that help to prevent the growth of cancer cells.
WAC has been shown to be highly reactive and can interact with a wide range of molecules. Its ability to form a coiled-coil structure allows it to interact with other proteins and molecules in a variety of ways. This interaction with other molecules makes WAC an attractive target for drug development.
The Potential of WAC as a Drug Target
WAC has been identified as a potential drug target for a variety of cancer types, including breast, ovarian, and colorectal cancers. Studies have shown that inhibiting WAC can lead to the regression of cancer tumors. This is because WAC plays a critical role in the regulation of cell growth and the control of apoptosis, which are processes that are often disrupted in cancer cells.
WAC has also been shown to be involved in the regulation of the immune response, which is an important factor in the fight against cancer. By regulating the immune response, WAC helps to ensure that the body is able to detect and destroy cancer cells before they can spread.
The Potential of WAC as a Biomarker
WAC has also been shown to be a potential biomarker for cancer. Its ability to interact with other proteins and molecules makes it an attractive target for diagnostic tests. For example, researchers have shown that WAC can be used as a marker for the diagnosis of breast cancer. This is because WAC is often expressed in the cells of breast tissue, and its levels can be used as a indicator of the presence of cancer.
WAC has also been shown to be a potential biomarker for ovarian cancer. This is because WAC is often expressed in the cells of ovarian tissue, and its levels can be used as a indicator of the presence of cancer.
Conclusion
In conclusion, WAC is a protein that plays a critical role in various biological processes, including cell-cell adhesion, cell growth, and apoptosis. Its ability to interact with other proteins and molecules makes it an attractive drug target or biomarker for the fight against cancer. As research continues to advance, it is likely that the use of WAC will become increasingly important in the development of new cancer treatments.
Protein Name: WW Domain Containing Adaptor With Coiled-coil
Functions: Acts as a linker between gene transcription and histone H2B monoubiquitination at 'Lys-120' (H2BK120ub1) (PubMed:21329877). Interacts with the RNA polymerase II transcriptional machinery via its WW domain and with RNF20-RNF40 via its coiled coil region, thereby linking and regulating H2BK120ub1 and gene transcription (PubMed:21329877). Regulates the cell-cycle checkpoint activation in response to DNA damage (PubMed:21329877). Positive regulator of amino acid starvation-induced autophagy (PubMed:22354037). Also acts as a negative regulator of basal autophagy (PubMed:26812014). Positively regulates MTOR activity by promoting, in an energy-dependent manner, the assembly of the TTT complex composed of TELO2, TTI1 and TTI2 and the RUVBL complex composed of RUVBL1 and RUVBL2 into the TTT-RUVBL complex. This leads to the dimerization of the mTORC1 complex and its subsequent activation (PubMed:26812014). May negatively regulate the ubiquitin proteasome pathway (PubMed:21329877)
The "WAC Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about WAC comprehensively, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
More Common Targets
WAC-AS1 | WAKMAR1 | WAKMAR2 | WAPL | WARS1 | WARS2 | WARS2-AS1 | WAS | WASF1 | WASF2 | WASF3 | WASF4P | WASF5P | WASH complex | WASH2P | WASH3P | WASH4P | WASH5P | WASH6P | WASH7P | WASH8P | WASHC1 | WASHC2A | WASHC2C | WASHC3 | WASHC4 | WASHC5 | WASIR1 | WASL | WAVE1 complex | WBP1 | WBP11 | WBP11P1 | WBP1L | WBP2 | WBP2NL | WBP4 | WDCP | WDFY1 | WDFY2 | WDFY3 | WDFY3-AS2 | WDFY4 | WDHD1 | WDPCP | WDR1 | WDR11 | WDR11-DT | WDR12 | WDR13 | WDR17 | WDR18 | WDR19 | WDR20 | WDR24 | WDR25 | WDR26 | WDR27 | WDR3 | WDR31 | WDR33 | WDR35 | WDR35-DT | WDR36 | WDR37 | WDR38 | WDR4 | WDR41 | WDR43 | WDR44 | WDR45 | WDR45B | WDR46 | WDR47 | WDR48 | WDR49 | WDR5 | WDR53 | WDR54 | WDR55 | WDR59 | WDR5B | WDR6 | WDR62 | WDR64 | WDR7 | WDR70 | WDR72 | WDR73 | WDR74 | WDR75 | WDR76 | WDR77 | WDR81 | WDR82 | WDR82P1 | WDR83 | WDR83OS | WDR86 | WDR86-AS1
