Retinoid acid receptor (nonspecified subtype)
Review Report on Retinoid acid receptor (nonspecified subtype) Target / Biomarker Content of Review Report on Retinoid acid receptor (nonspecified subtype) Target / Biomarker
Retinoid acid receptor (nonspecified subtype)

Related Diseases

1) Arthritis
Arthritis, also known as inflammatory joint disease, is related to rheumatoid arthritis and juvenile rheumatoid arthritis, and has symptoms including arthralgia, back pain and metatarsalgia. An important gene associated with Arthritis is SYK (Spleen Associated Tyrosine Kinase), and among its related pathways/superpathways are Innate Immune System and MIF Mediated Glucocorticoid Regulation. The drugs Entecavir and Chlorhexidine have been mentioned in the context of this disorder. Affiliated tissues include joint, bone and bone marrow, and related phenotypes are Decreased Tat-dependent HIV-LTR-beta-galactosidase protein expression and homeostasis/metabolism

2) Metabolic Diseases
3-Hydroxyacyl-Coa Dehydrogenase Deficiency, also known as hadh deficiency, is related to long-chain 3-hydroxyacyl-coa dehydrogenase deficiency and hyperinsulinemic hypoglycemia, familial, 4, and has symptoms including emaciation An important gene associated with 3-Hydroxyacyl-Coa Dehydrogenase Deficiency is HADH (Hydroxyacyl-CoA Dehydrogenase). The drugs Naloxone and Buprenorphine have been mentioned in the context of this disorder. Affiliated tissues include liver, heart and skeletal muscle, and related phenotypes are feeding difficulties in infancy and growth delay

3) Toxic Epidermal Necrolysis
Severe Cutaneous Adverse Reaction, also known as stevens-johnson syndrome, is related to sjogren syndrome and viral infectious disease. An important gene associated with Severe Cutaneous Adverse Reaction is HLA-B (Major Histocompatibility Complex, Class I, B), and among its related pathways/superpathways are NF-kappaB Signaling and Apoptosis and Autophagy. The drugs Miconazole and Clotrimazole have been mentioned in the context of this disorder. Affiliated tissues include skin, eye and salivary gland, and related phenotypes are nausea and vomiting and dysphagia

4) Infertility, Male
Male Infertility, also known as infertility, male, is related to spermatogenic failure 9 and infertility, and has symptoms including subfertility, male, inability to conceive due to male infertility and inability to impregnate. An important gene associated with Male Infertility is CFTR (CF Transmembrane Conductance Regulator), and among its related pathways/superpathways are Male infertility and Ovarian infertility. The drugs Progesterone and Dydrogesterone have been mentioned in the context of this disorder. Affiliated tissues include Testis, and related phenotypes are no effect and no effect

5) Kaposi Sarcoma
Kaposi Sarcoma, also known as kaposi's sarcoma, is related to sarcoma and acquired immunodeficiency syndrome, and has symptoms including exanthema, pruritus and fever. An important gene associated with Kaposi Sarcoma is IL6 (Interleukin 6), and among its related pathways/superpathways are Innate Immune System and Disease. The drugs Bleomycin and Lopinavir have been mentioned in the context of this disorder. Affiliated tissues include skin, lung and lymph node, and related phenotypes are recurrent herpes and neoplasm of the skin

6) Leukoplakia, Oral
Oral Mucosa Leukoplakia, also known as leukoplakia of buccal mucosa, is related to leukoplakia and lichen planus. An important gene associated with Oral Mucosa Leukoplakia is TEC (Tec Protein Tyrosine Kinase). The drugs Rosiglitazone and Celecoxib have been mentioned in the context of this disorder.

7) Neuroblastoma
Neuroblastoma, also known as nb, is related to differentiating neuroblastoma and glioma, and has symptoms including back pain, headache and pain. An important gene associated with Neuroblastoma is ALK (ALK Receptor Tyrosine Kinase). The drugs Nicotine and Miconazole have been mentioned in the context of this disorder. Affiliated tissues include adrenal gland, bone marrow and spinal cord, and related phenotypes are neoplasm of the nervous system and elevated urinary catecholamines

8) Eczema
Dermatitis, also known as eczema, is related to irritant dermatitis and dermatitis herpetiformis, and has symptoms including exanthema and pruritus. An important gene associated with Dermatitis is FLG (Filaggrin), and among its related pathways/superpathways are Innate Immune System and MIF Mediated Glucocorticoid Regulation. The drugs Salicylic acid and Titanium dioxide have been mentioned in the context of this disorder. Affiliated tissues include skin, breast and t cells, and related phenotypes are immune system and hematopoietic system

9) Atopic Dermatitis
Dermatitis, Atopic, also known as atopic dermatitis, is related to allergic disease and dermatitis, atopic, 3, and has symptoms including exanthema and pruritus. An important gene associated with Dermatitis, Atopic is FLG (Filaggrin), and among its related pathways/superpathways are MIF Mediated Glucocorticoid Regulation and Cytokine Signaling in Immune system. The drugs Zinc oxide and Coal tar have been mentioned in the context of this disorder. Affiliated tissues include skin, t cells and breast, and related phenotypes are cataract and ichthyosis

10) Cancer, Lung
Lung Cancer, also known as non-small cell lung carcinoma, is related to lung cancer susceptibility 3 and small cell cancer of the lung, and has symptoms including cough, chest discomfort and weight loss. An important gene associated with Lung Cancer is BRAF (B-Raf Proto-Oncogene, Serine/Threonine Kinase), and among its related pathways/superpathways are Innate Immune System and Apoptotic Pathways in Synovial Fibroblasts. The drugs Pemetrexed and Erlotinib have been mentioned in the context of this disorder. Affiliated tissues include lung, lungs and brain, and related phenotypes are lung adenocarcinoma and alveolar cell carcinoma

11) Leukemia
Leukemia, also known as leukaemia, unspecified, without mention of remission, is related to myeloid leukemia and leukemia, chronic myeloid, and has symptoms including angina pectoris, chest pain and edema. An important gene associated with Leukemia is MIR27A (MicroRNA 27a), and among its related pathways/superpathways are NF-kappaB Signaling and Imatinib and chronic myeloid leukemia. The drugs Azacitidine and Decitabine have been mentioned in the context of this disorder. Affiliated tissues include myeloid, bone marrow and t cells, and related phenotypes are Increased HDAC inhibitor resistance and endocrine/exocrine gland

12) Cutaneous Lupus Erythematosus
Cutaneous Lupus Erythematosus, also known as lupus erythematosus, cutaneous, is related to subacute cutaneous lupus erythematosus and familial chilblain lupus, and has symptoms including exanthema and pruritus. An important gene associated with Cutaneous Lupus Erythematosus is CXCR3 (C-X-C Motif Chemokine Receptor 3), and among its related pathways/superpathways are Innate Immune System and Interferon gamma signaling. The drugs Hydroxychloroquine and Anti-Infective Agents have been mentioned in the context of this disorder. Affiliated tissues include skin, heart and t cells, and related phenotypes are immune system and hematopoietic system

13) Acne
Acne, also known as acne vulgaris, is related to sapho syndrome and hidradenitis suppurativa, and has symptoms including exanthema and pruritus. An important gene associated with Acne is NCSTN (Nicastrin), and among its related pathways/superpathways are Innate Immune System and Prolactin Signaling. The drugs Calcipotriol and Adapalene have been mentioned in the context of this disorder. Affiliated tissues include skin, ovary and thyroid, and related phenotypes are no effect and no effect

14) Obesity
Body Mass Index Quantitative Trait Locus 11, also known as obesity, is related to leptin deficiency or dysfunction and type 2 diabetes mellitus, and has symptoms including high weight, symptoms and obesity, metabolically benign. An important gene associated with Body Mass Index Quantitative Trait Locus 11 is UCP3 (Uncoupling Protein 3), and among its related pathways/superpathways are Beta-2 adrenergic-dependent CFTR expression and Glucose / Energy Metabolism. The drugs Hydrocortisone and Hydrocortisone succinate have been mentioned in the context of this disorder. Affiliated tissues include skeletal muscle, liver and heart, and related phenotypes are obesity and decreased resting energy expenditure

15) Keratosis, Actinic
Actinic Keratosis, also known as solar keratosis, is related to keratosis and squamous cell carcinoma. An important gene associated with Actinic Keratosis is TP63 (Tumor Protein P63), and among its related pathways/superpathways are Toll-like receptor signaling pathway and Toll-Like receptor Signaling Pathways. The drugs Prilocaine and Bacitracin have been mentioned in the context of this disorder. Affiliated tissues include skin, kidney and liver, and related phenotypes are endocrine/exocrine gland and neoplasm

16) Hyperkeratosis
Palmoplantar Keratoderma, Epidermolytic, also known as epidermolytic palmoplantar keratoderma, is related to palmoplantar keratoderma, nonepidermolytic, focal or diffuse and palmoplantar keratoderma, nonepidermolytic. An important gene associated with Palmoplantar Keratoderma, Epidermolytic is KRT9 (Keratin 9), and among its related pathways/superpathways are Nervous system development and Keratinization. The drugs Antibodies and Immunoglobulins have been mentioned in the context of this disorder. Affiliated tissues include skin, breast and heart, and related phenotypes are epidermal hyperkeratosis and abnormal fingernail morphology

17) Psoriasis
Psoriasis is related to psoriasis 7 and psoriasis 10, and has symptoms including exanthema, pruritus and psoriasiform rash. An important gene associated with Psoriasis is MIR203A (MicroRNA 203a), and among its related pathways/superpathways are miRNAs involvement in the immune response in sepsis and Cell differentiation - expanded index. The drugs Metformin and Vedolizumab have been mentioned in the context of this disorder. Affiliated tissues include skin, t cells and endothelial.

18) Osteoarthritis
Osteoarthritis, also known as osteoarthrosis, is related to cartilage disease and exostosis, and has symptoms including arthralgia, back pain and metatarsalgia. An important gene associated with Osteoarthritis is HOTAIR (HOX Transcript Antisense RNA), and among its related pathways/superpathways are ECM proteoglycans and Extracellular matrix organization. The drugs Fentanyl and Benzocaine have been mentioned in the context of this disorder. Affiliated tissues include Cartilage and Bone, and related phenotype is limbs/digits/tail.

19) Ichthyosis
Ichthyosis, also known as ichthyoses, is related to ichthyosis, congenital, autosomal recessive 4b and autosomal recessive congenital ichthyosis, and has symptoms including trichorrhexis invaginata An important gene associated with Ichthyosis is TGM1 (Transglutaminase 1), and among its related pathways/superpathways are Keratinization and Prostaglandin 2 biosynthesis and metabolism FM. The drugs Ustekinumab and Emollients have been mentioned in the context of this disorder. Affiliated tissues include skin, neutrophil and lymph node, and related phenotypes are homeostasis/metabolism and growth/size/body region

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More Common Targets

11beta-Hydroxysteroid Dehydrogenase | 14-3-3 Protein | 15-Lipoxygenase | 17-beta-Hydroxysteroid dehydrogenase | 28S ribosomal subunit, mitochondrial | 3-Ketoacyl-CoA Thiolase (3-KAT) | 39S ribosomal subunit, mitochondrial | 4EHP-GYF2 complex | 5-Hydroxytryptamine Receptor | 5-Hydroxytryptamine Receptor 1 (5-HT1) | 5-Hydroxytryptamine Receptor 2 (5-HT2) | 60S Ribosome | 9-1-1 cell-cycle checkpoint response complex | A-Kinase Anchor Proteins | A1BG | A1BG-AS1 | A1CF | A2M | A2M-AS1 | A2ML1 | A2MP1 | A3GALT2 | A4GALT | A4GNT | AAAS | AACS | AACSP1 | AADAC | AADACL2 | AADACL2-AS1 | AADACL3 | AADACL4 | AADACP1 | AADAT | AAGAB | AAK1 | AAMDC | AAMP | AANAT | AAR2 | AARD | AARS1 | AARS2 | AARSD1 | AASDH | AASDHPPT | AASS | AATBC | AATF | AATK | ABALON | ABAT | ABCA1 | ABCA10 | ABCA11P | ABCA12 | ABCA13 | ABCA17P | ABCA2 | ABCA3 | ABCA4 | ABCA5 | ABCA6 | ABCA7 | ABCA8 | ABCA9 | ABCB1 | ABCB10 | ABCB11 | ABCB4 | ABCB5 | ABCB6 | ABCB7 | ABCB8 | ABCB9 | ABCC1 | ABCC10 | ABCC11 | ABCC12 | ABCC13 | ABCC2 | ABCC3 | ABCC4 | ABCC5 | ABCC6 | ABCC6P1 | ABCC6P2 | ABCC8 | ABCC9 | ABCD1 | ABCD2 | ABCD3 | ABCD4 | ABCE1 | ABCF1 | ABCF1-DT | ABCF2 | ABCF3 | ABCG1 | ABCG2

Disease Target / Biomarker