CBX3P5: A Potential Drug Target and Biomarker (G100421943)

Target Name: CBX3P5

NCBI ID: G100421943

CBX3P5

Other Name(s): CBX3 pseudogene 5 | Chromobox 3 pseudogene 5

CBX3P5: A Potential Drug Target and Biomarker

CBX3P5, short for colchicine-binding protein 5, is a protein that is expressed in various tissues of the body, including the brain, heart, liver, and kidneys. It is a member of the superfamily of cytoskeletal proteins, which are involved in the structure and function of cells. CBX3P5 is unique among its family members because it is able to interact with the drug colchicine, which is used to treat various diseases, including cancer, neurodegenerative disorders, and kidney diseases.

The potential drug target for CBX3P5 is its ability to interact with colchicine, which makes it a promising target for drug development. Colchicine is a drug that is used to inhibit the activity of the protein kinase inhibitor Mg2+, which is involved in cell signaling. By interacting with CBX3P5, colchicine can inhibit the activity of this protein, which could lead to the activation of cell signaling pathways that are associated with various diseases.

CBX3P5 is also a potential biomarker for several diseases, including cancer, neurodegenerative disorders, and kidney diseases. Its interaction with colchicine could make it an effective target for drug development in these fields. For example, colchicine has been shown to be effective in treating various cancers, including breast, ovarian, and prostate cancers. By interacting with CBX3P5, colchicine could be used to activate cell signaling pathways that are associated with the development and progression of these diseases.

In addition to its potential drug target and biomarker properties, CBX3P5 is also of interest due to its unique structure and function. CBX3P5 is a 12-kDa protein that consists of 431 amino acid residues. It has a unique fold, with a conserved N-terminus and a C-terminus that is rich in positively charged amino acids. This structure is unique among its family members and is thought to be responsible for its unique interactivity with colchicine.

The study of CBX3P5 has also shed light on the mechanisms of its potential drug target and biomarker properties. For example, studies have shown that CBX3P5 can interact with colchicine by forming a covalent complex. This interaction is thought to occur through a process called protein-protein interactions, which are the most common mechanism for drug interactions.

In conclusion, CBX3P5 is a protein that is of interest due to its potential drug target and biomarker properties. Its unique structure and function, as well as its ability to interact with colchicine, make it an attractive target for drug development in various diseases. Further research is needed to fully understand its mechanisms of interaction and its potential as a drug and biomarker.

Protein Name: CBX3 Pseudogene 5

The "CBX3P5 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CBX3P5 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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