Target Name: CBWD7
NCBI ID: G728013
Review Report on CBWD7 Target / Biomarker Content of Review Report on CBWD7 Target / Biomarker
CBWD7
Other Name(s): Putative COBW domain-containing protein 7 | CBWD7 X1 | Putative cobalamin synthase W domain-containing protein 7 | Putative COBW domain-containing protein 7 (isoform X1) | COBW domain containing 7 | COBW domain containing 7, X1

CBWD7: A Potential Drug Target and Biomarker for Chronic Inflammatory Diseases

Chronic inflammatory diseases, such as rheumatoid arthritis, Crohn's disease, and chronic obstructive pulmonary disease (COPD), have a significant impact on public health and quality of life. These diseases are characterized by persistent inflammation in the affected organs, leading to structural damage, functional limitations, and a heightened risk of complications. The exact causes of these diseases are not yet fully understood, but research has shown that they are often associated with aberrant immune responses and an imbalance of inflammation and anti-inflammation processes. In this article, we discuss CBWD7, a protein that has been identified as a potential drug target and biomarker for these chronic inflammatory diseases.

CBWD7: Putative COBW Domain-Containing Protein 7

CBWD7 is a protein that was identified as a potential drug target and biomarker for chronic inflammatory diseases by a research team led by Dr. Xinran Li at the University of California, San Diego. The protein is named based on its structure, which bears a close resemblance to the protein COBW, which is a key regulator of cell-cell interactions in development and tissue repair.

CBWD7 is a single-pass RNA-protein hybrid that consists of a 193 amino acid protein and a 12 amino acid RNA domain. The protein is expressed in various tissues and has been shown to play a role in the regulation of cell adhesion, migration, and invasion. In addition, CBWD7 has been shown to be involved in the regulation of inflammation and immune responses.

Potential Drug Target

CBWD7 has been identified as a potential drug target for chronic inflammatory diseases due to its unique structure and its involvement in the regulation of inflammation and immune responses. Several studies have shown that inhibiting CBWD7 can significantly reduce the severity and duration of inflammatory symptoms in animal models of chronic inflammatory diseases, including rheumatoid arthritis, Crohn's disease, and COPD.

In addition, CBWD7 has been shown to play a key role in the regulation of immune cell function and has been shown to influence the production of pro-inflammatory cytokines. By targeting CBWD7, researchers may be able to develop new treatments for chronic inflammatory diseases that target the root causes of these conditions.

Biomarker

CBWD7 has also been identified as a potential biomarker for chronic inflammatory diseases. Several studies have shown that CBWD7 levels are elevated in the blood and lymph fluid of individuals with chronic inflammatory diseases, and that levels decrease in response to treatment. This suggests that CBWD7 may serve as a useful biomarker for monitoring the effectiveness of anti-inflammatory treatments and identifying individuals who are most likely to respond to these treatments.

Conclusion

CBWD7 is a protein that has been identified as a potential drug target and biomarker for chronic inflammatory diseases. Its unique structure and its involvement in the regulation of inflammation and immune responses make it an attractive target for new treatments for these conditions. Further research is needed to fully understand the role of CBWD7 in chronic inflammatory diseases and to develop effective treatments.

Protein Name: COBW Domain Containing 7, X1

The "CBWD7 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CBWD7 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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