CATSPERZ: A Potential Drug Target and Biomarker for the Treatment of Chronic Pain

Target Name: CATSPERZ

NCBI ID: G25858

CATSPERZ

CATSPERZ: A Potential Drug Target and Biomarker for the Treatment of Chronic Pain

Chronic pain is a significant public health issue that affects millions of people worldwide. The World Health Organization (WHO) estimates that 57 million adults experience chronic pain, and this number is projected to increase to 95 million by 2030. Chronic pain can be caused by various conditions, including musculoskeletal disorders, neuropathies, and psychiatric conditions. The symptoms of chronic pain can range from mild to severe and can significantly impact an individual's quality of life.

CATSPERZ, or CatSper-zeta, is a protein that has been identified as a potential drug target and biomarker for the treatment of chronic pain. CATSPERZ is a cytoskeleton-associated protein that is expressed in various tissues and cells, including neural cells, muscle cells, and blood vessels. CATSPERZ has been shown to play a role in the regulation of cell signaling pathways that are involved in pain perception and chronic pain management.

Drug Target Potential

CATSPERZ has been identified as a potential drug target due to its involvement in several pain-related signaling pathways. The pain signaling pathway is complex and involves various signaling molecules. CATSPERZ has been shown to be involved in the regulation of the following pain-related signaling pathways:

1. Fibrotic signaling pathway: CATSPERZ has been shown to be involved in the regulation of fibrotic signaling pathways, which are involved in the production of extracellular matrix (ECM) components that can contribute to pain perception.
2. Neuropeptide signaling pathway: CATSPERZ has been shown to be involved in the regulation of neuropeptide signaling pathways, which are involved in the production and release of chemical messengers that can contribute to pain perception.
3. Pain modulation by microRNA (miRNA) pathway: CATSPERZ has been shown to be involved in the regulation of miRNA pathways, which are involved in the production and degradation of small non-coding RNAs that can regulate gene expression and cell signaling.

Biomarker Potential

CATSPERZ has also been identified as a potential biomarker for the diagnosis and monitoring of chronic pain. The evaluation of pain using physiological measures, such as the use of pain rating scales, is often limited by the availability of subjective pain scores. CATSPERZ has been shown to be involved in the regulation of pain perception, which can be used as a potential biomarker for the diagnosis of chronic pain.

Expression and Localization of CATSPERZ

CATSPERZ is a cytoskeleton-associated protein that is expressed in various tissues and cells, including neural cells, muscle cells, and blood vessels. CATSPERZ has been shown to be involved in the regulation of cell signaling pathways that are involved in pain perception and chronic pain management.

CATSPERZ has been shown to be expressed in various tissues and cells, including the brain, spinal cord, and peripheral tissues. CATSPERZ has been shown to be involved in the regulation of neural cell proliferation and differentiation, and has been shown to play a role in the development and progression of neural disorders, such as Alzheimer's disease and Parkinson's disease.

CATSPERZ has also been shown to be involved in the regulation of muscle cell function and has been shown to play a role in the development and progression of muscle disorders, such as dystonia and myotonic dystrophy.

CATSPERZ has also been shown to be involved in the regulation of blood vessel function and has been shown to play

Protein Name: Catsper Channel Auxiliary Subunit Zeta

Functions: Auxiliary component of the CatSper complex, a complex involved in sperm cell hyperactivation. Sperm cell hyperactivation is needed for sperm motility which is essential late in the preparation of sperm for fertilization. Required for a distribution of the CatSper complex in linear quadrilateral nanodomains along the flagellum, maximizing fertilization inside the mammalian female reproductive tract. Together with EFCAB9, associates with the CatSper channel pore and is required for the two-row structure of each single CatSper channel

The "CATSPERZ Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CATSPERZ comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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