Target Name: G2E3
NCBI ID: G55632
Review Report on G2E3 Target / Biomarker Content of Review Report on G2E3 Target / Biomarker
G2E3
Other Name(s): G2/M-phase specific E3 ubiquitin protein ligase, transcript variant 1 | KIAA1333 | PHF7B | G2/M-phase specific E3 ubiquitin ligase | PHD finger protein 7B | G2/M-phase specific E3 ubiquitin protein ligase | G2/M phase-specific E3 ubiquitin-protein ligase | G2E3_HUMAN | G2/M phase-specific E3 ubiquitin-protein ligase (isoform 1) | G2E3 variant 1 | G2/M phase-specific HECT-type E3 ubiquitin transferase

G2E3: Key Player in Ubiquitin System

G2E3 (G2/M-phase specific E3 ubiquitin protein ligase, transcript variant 1) is a protein that is expressed in various tissues and cells throughout the body. It is a key player in the ubiquitin system, a protein-protein interaction network that plays a crucial role in various cellular processes, including cell signaling, DNA damage repair, and inflammation. G2E3 is also known as E3 ubiquitin protein ligase, transcript variant 1.

G2E3 is a 21-kDa protein that consists of 21 amino acid residues. It belongs to the E3 ubiquitin family, which is characterized by the presence of a characteristic Rossmann-fold in the protein sequence. This family plays a central role in the regulation of various cellular processes, including DNA damage repair, cell signaling, and inflammation.

G2E3 is expressed in various tissues and cells throughout the body, including the liver, lung, heart, kidney, and pancreas. It is also expressed in the placenta, which supports the development and maintenance of fetal tissues. G2E3 is involved in the ubiquitin system, which is a protein-protein interaction network that plays a crucial role in various cellular processes.

G2E3 is involved in the regulation of various cellular processes, including cell signaling, DNA damage repair, and inflammation. It is a key player in the ubiquitin system, which is a protein-protein interaction network that plays a crucial role in

Protein Name: G2/M-phase Specific E3 Ubiquitin Protein Ligase

Functions: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Essential in early embryonic development to prevent apoptotic death

The "G2E3 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about G2E3 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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