Target Name: G6PC2
NCBI ID: G57818
Review Report on G6PC2 Target / Biomarker Content of Review Report on G6PC2 Target / Biomarker
G6PC2
Other Name(s): G6PC2_HUMAN | Glucose-6-phosphatase catalytic 2 | glucose-6-phosphatase catalytic subunit 2 | IGRP | glucose-6-phosphatase, catalytic, 2 | Glucose-6-phosphatase 2 | Glucose-6-phosphatase 2 (isoform 1) | islet-specific G6CP-related protein | G-6-Pase 2 | G6PC2 variant 1 | islet-specific glucose-6-phosphatase catalytic subunit-related protein | islet-specific glucose-6-phosphatase-related protein | G6Pase 2 | Glucose-6-phosphatase catalytic subunit 2, transcript variant 1 | Islet-specific glucose-6-phosphatase catalytic subunit-related protein

G6PC2: A Potential Drug Target and Biomarker for Diabetes and Other Diseases

G6PC2 (G6PC2_HUMAN) is a gene that encodes a protein known as glucose-6-phosphate dehydrogenase (G6PCase), which is an enzyme involved in the metabolism of glucose. G6PCase is a key enzyme in the liver, where it converts glucose-6-phosphate (G6P) to glucose (Glucose), which is the primary source of energy for the body.

G6PC2 is a protein that is expressed in many different tissues throughout the body, including the liver, kidneys, heart, and muscles. It is also highly expressed in the placenta, which is responsible for providing glucose to the developing fetus.

G6PC2 has been identified as a potential drug target for a variety of diseases, including diabetes, heart failure, and hypoglycemia (low blood sugar). It is also been shown to be involved in a variety of cellular processes, including cell signaling, metabolism, and inflammation.

One of the unique features of G6PC2 is its ability to interact with a variety of different molecules, including transcription factors, enzymes, and hormones. This makes it an attractive target for drug development, as it allows for the use of a wide range of potential therapeutic approaches.

G6PC2 has also been shown to play a role in the regulation of cellular processes that are important for human health, including metabolism, inflammation, and aging. For example, studies have shown that G6PC2 is involved in the regulation of muscle growth and function, and that it plays a role in the development of age-related muscle loss.

In addition to its potential therapeutic applications, G6PC2 is also a valuable biomarker for a variety of diseases. For example, it has been shown to be elevated in the blood of people with type 2 diabetes, and it has been used as a diagnostic marker for this disease. Additionally, G6PC2 has been shown to be elevated in the blood of people with heart failure, which is a condition in which the heart is not able to pump enough blood to meet the body's needs.

Overall, G6PC2 is a protein that has the potential to be a valuable drug target and biomarker for a variety of diseases. Further research is needed to fully understand its role in the body and its potential as a therapeutic approach.

Protein Name: Glucose-6-phosphatase Catalytic Subunit 2

Functions: May hydrolyze glucose-6-phosphate to glucose in the endoplasmic reticulum. May be responsible for glucose production through glycogenolysis and gluconeogenesis (By similarity)

The "G6PC2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about G6PC2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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