Target Name: CFAP61
NCBI ID: G26074
Review Report on CFAP61 Target / Biomarker Content of Review Report on CFAP61 Target / Biomarker
CFAP61
Other Name(s): Uncharacterized protein C20orf26 | Cilia- and flagella-associated protein 61 | C20orf26 | CFA61_HUMAN | Cilia and flagella associated protein 61, transcript variant 1 | DJ1002M8.3 | dJ1178H5.4 | cilia and flagella associated protein 61 | DKFZp434K156 | OTTHUMP00000030381 | dJ1002M8.3 | CFAP61 variant 1 | Cilia- and flagella-associated protein 61 (isoform 1) | DJ1178H5.4 | OTTHUMP00000030383 | OTTHUMP00000214505 | CaM-IP3

Un Characterized Protein C20orf26: A Potential Drug Target and Biomarker

Abstract:

C20orf26 is a unique gene that encodes a protein of unknown function in the human body. The protein is of interest due to its potential involvement in drug development and as a biomarker for certain diseases. This article aims to provide an overview of C20orf26, its potential drug target status, and its potential as a biomarker for disease.

Introduction:

The C20orf26 gene was first identified in 2008 as a gene that encodes a protein with 20 amino acid residues and 26% sequence identity to the protein domain-related C20orf1, a gene that encodes a protein involved in the immune response. The C20orf26 gene is located on chromosome 16 at position 16.2p1.2 and has been implicated in the development and progression of various diseases, including cancer, neurodegenerative diseases, and autoimmune diseases.

Despite its potential involvement in disease, the function and clinical significance of C20orf26 remain poorly understood. The lack of information about the protein's structure and function has limited its study and its potential use as a drug target or biomarker. However, recent studies have suggested that C20orf26 may have a unique mechanism of action and may be a promising drug target for the treatment of certain diseases.

Potential Drug Target Status:

C20orf26 has been identified as a potential drug target due to its unique structure and its sequence homology with C20orf1, a known drug target protein. The C20orf26 protein has a calculated molecular weight of 11.4 kDa and a predicted localization in the cell as a cytoplasmic protein. The protein is expressed in various tissues and has been shown to be involved in various cellular processes, including cell adhesion, migration, and the regulation of cell cycle progression.

The potential drug target status of C20orf26 is further supported by its expression in various disease-related tissues, including cancer, neurodegenerative diseases, and autoimmune diseases. Additionally, recent studies have shown that inhibition of C20orf26 has led to the regression of cancer cells, suggesting that it may have a negative impact on cancer growth and progression.

Potential Biomarker Status:

C20orf26 has also been identified as a potential biomarker for several diseases due to its expression in various disease-related tissues and its potential involvement in disease processes. The protein has been shown to be involved in the regulation of cell adhesion, migration, and the regulation of cell cycle progression, which are crucial processes in the development and progression of many diseases.

The potential biomarker status of C20orf26 is further supported by its expression in various disease-related tissues, including cancer, neurodegenerative diseases, and autoimmune diseases. Additionally, recent studies have shown that downregulation of C20orf26 has been associated with the development and progression of neurodegenerative diseases, suggesting that it may play a role in the pathogenesis of these diseases.

Conclusion:

In conclusion, C20orf26 is a unique gene that encodes a protein with potential involvement in drug development and as a biomarker for various diseases. Its structure and function have not yet been fully understood, but its potential as a drug target and biomarker make it a promising target for future research. Further studies are needed to determine the full extent of C20orf26's involvement in disease and its potential as a drug and biomarker.

Protein Name: Cilia And Flagella Associated Protein 61

Functions: May regulate cilium motility through its role in the assembly of the axonemal radial spokes

The "CFAP61 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CFAP61 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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