GNB4 Plays A Crucial Role in Intracellular Signaling and Has Potential as A Drug Target

Target Name: GNB4

NCBI ID: G59345

GNB4

GNB4 Plays A Crucial Role in Intracellular Signaling and Has Potential as A Drug Target

Guanine nucleotide binding proteins (GNPs) are a family of transmembrane proteins that play a crucial role in intracellular signaling. Guanine nucleotide binding protein (also known as GNB4) is a G protein that is expressed in various tissues and cells and is known for its unique structure and function. GNP-尾 is a protein that can interact with the protein G尾1, which is a key regulator of the Guanine nucleotide-binding protein (G protein) signaling pathway.

The G protein signaling pathway is a well-established pathway that involves the interaction between G伪-proteins and GTP-binding proteins (GKPs). The G尾1 protein is a GKP that plays a critical role in regulating the activity of the G protein. G尾1 can interact with various G proteins, including GNP-尾, to regulate the activity of these proteins.

GNP-尾 is a 21-kDa protein that is expressed in various tissues and cells, including the heart, pancreas, and brain. It is characterized by a unique structure that includes a long N-terminus, a catalytic domain, and a short C-terminus. The N-terminus of GNP-尾 contains a unique farnesylated cysteine residue, which is important for its stability and function.

GNP-尾 has been shown to play a critical role in various physiological processes, including cell signaling, metabolism, and inflammation. It is involved in the regulation of a wide range of cellular processes, including cell adhesion, migration, and the regulation of ion channels. GNP-尾 has also been shown to play a role in the regulation of inflammation and has been shown to be involved in the regulation of pain perception.

GNP-尾 has also been shown to be a potential drug target. Several studies have shown that GNP-尾 can be targeted by small molecules, including inhibitors of the protein kinase C (PKC) and the protein tyrosine phosphatase (PTP). These inhibitors have been shown to inhibit the activity of GNP-尾 and to reduce the production of G尾1.

In addition to its potential as a drug target, GNP-尾 is also a potential biomarker. The activity of GNP-尾 has been shown to be regulated by various factors, including the levels of intracellular GTP, the activity of PKC, and the levels of G尾1. Therefore, changes in the levels of GNP-尾 or its activity can be used as a potential biomarker for a variety of diseases, including cancer, neurodegenerative diseases, and cardiovascular disease.

GNP-尾 is also involved in the regulation of cellular signaling pathways that are important for maintaining cellular homeostasis. For example, GNP-尾 has been shown to be involved in the regulation of the production of reactive oxygen species (ROS), which can cause damage to cellular components and contribute to the development of oxidative stress diseases.

In conclusion, GNP-尾 is a unique and highly regulated protein that plays a critical role in intracellular signaling. Its unique structure and function make it an attractive target for small molecules, including inhibitors of the protein kinase C and the protein tyrosine phosphatase. In addition to its potential as a drug target, GNP-尾 is also a potential biomarker for a variety of diseases. Further research is needed to fully understand the role of GNP-尾 in cellular signaling and its potential as a drug and biomarker.

Protein Name: G Protein Subunit Beta 4

Functions: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction

The "GNB4 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about GNB4 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets