Target Name: GNG12
NCBI ID: G55970
Review Report on GNG12 Target / Biomarker Content of Review Report on GNG12 Target / Biomarker
GNG12
Other Name(s): GBG12_HUMAN | FLJ31352 | guanine nucleotide binding protein (G protein), gamma 12 | HG3A | G protein subunit gamma 12 | Guanine nucleotide binding protein (G protein) gamma 12 | heterotrimeric guanine nucleotide-binding protein 3A | OTTHUMP00000011139 | G-protein gamma-12 subunit | FLJ34695 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12

GNG12: A Non-Coding RNA Regulator of Gene Expression and Potential Target Drug or Biomarker

GNG12 (Guanosine N-Methyltransferase 12) is a gene that encodes a protein known as GNG12 (GBG12_HUMAN). GNG12 is a non-coding RNA molecule that plays a role in the regulation of gene expression. It is expressed in a variety of tissues and cells throughout the body, including the brain, heart, liver, and muscle.

GNG12 is a key regulator of gene expression and has been implicated in the development and progression of a number of diseases. For example, GNG12 has been shown to be involved in the regulation of cell proliferation, and is often expressed in tissues that are highly dependent on cell growth for their survival.

In addition to its role in cell proliferation, GNG12 is also involved in the regulation of cell survival and lifespan. It has been shown to play a role in the regulation of apoptosis, which is the process by which cells undergo programmed cell death.

GNG12 is also involved in the regulation of cellular signaling pathways. For example, it has been shown to play a role in the regulation of the blood-brain barrier, which is the barrier that separates the brain from the blood and is responsible for ensuring that only certain substances are able to enter the brain.

In addition to its role in cellular signaling pathways, GNG12 is also involved in the regulation of gene expression. It has been shown to play a role in the regulation of the expression of other genes, including some that are involved in the development and progression of cancer.

GNG12 is also a potential drug target. Researchers have identified a number of potential drug targets for GNG12, including those that are involved in the regulation of cell proliferation, the regulation of apoptosis, and the regulation of cellular signaling pathways.

In addition to its potential as a drug target, GNG12 is also a potential biomarker. Researchers have shown that GNG12 is able to be used as a diagnostic biomarker for a number of diseases, including cancer, neurodegenerative diseases, and cardiovascular disease.

Overall, GNG12 is a gene that has the potential to be a drug target and a biomarker. Further research is needed to fully understand its role in the regulation of gene expression and its potential as a therapeutic agent.

Protein Name: G Protein Subunit Gamma 12

Functions: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction

The "GNG12 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about GNG12 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

GNG12-AS1 | GNG13 | GNG2 | GNG3 | GNG4 | GNG5 | GNG5P5 | GNG7 | GNG8 | GNGT1 | GNGT2 | GNL1 | GNL2 | GNL3 | GNL3L | GNLY | GNMT | GNPAT | GNPDA1 | GNPDA2 | GNPNAT1 | GNPTAB | GNPTG | GNRH1 | GNRH2 | GNRHR | GNRHR2 | GNS | GOLGA1 | GOLGA2 | GOLGA2P10 | GOLGA2P11 | GOLGA2P2Y | GOLGA2P5 | GOLGA2P7 | GOLGA3 | GOLGA4 | GOLGA5 | GOLGA6A | GOLGA6B | GOLGA6C | GOLGA6D | GOLGA6EP | GOLGA6FP | GOLGA6L1 | GOLGA6L10 | GOLGA6L2 | GOLGA6L22 | GOLGA6L3P | GOLGA6L4 | GOLGA6L5P | GOLGA6L6 | GOLGA6L9 | GOLGA7 | GOLGA7B | GOLGA8A | GOLGA8B | GOLGA8CP | GOLGA8DP | GOLGA8EP | GOLGA8F | GOLGA8G | GOLGA8H | GOLGA8IP | GOLGA8J | GOLGA8K | GOLGA8M | GOLGA8N | GOLGA8O | GOLGA8Q | GOLGA8R | GOLGA8S | GOLGA8UP | GOLGB1 | Golgi-associated retrograde protein (GARP) complex | GOLIM4 | GOLM1 | GOLM2 | GOLPH3 | GOLPH3L | GOLT1A | GOLT1B | GON4L | GON7 | GOPC | GORAB | GORASP1 | GORASP2 | GOSR1 | GOSR2 | GOT1 | GOT1-DT | GOT1L1 | GOT2 | GOT2P1 | GP1BA | GP1BB | GP2 | GP5 | GP6