Target Name: NDC1
NCBI ID: G55706
Review Report on NDC1 Target / Biomarker Content of Review Report on NDC1 Target / Biomarker
NDC1
Other Name(s): TMEM48 | transmembrane protein 48 | OTTHUMP00000009747 | FLJ34120 | hNDC1 | Nucleoporin NDC1 | FLJ12556 | Nucleoporin NDC1 (isoform 2) | NDC1 transmembrane nucleoporin | FLJ10407 | NDC1 variant 2 | Nucleoporin NDC1 (isoform 1) | NDC1_HUMAN | NDC1 variant 1 | NET3 | Transmembrane protein 48 | NDC1 transmembrane nucleoporin, transcript variant 2 | nuclear division cycle 1 homolog | NDC1 transmembrane nucleoporin, transcript variant 1

NDC1: A Protein with Potential as A Drug Target Or Biomarker

NDC1 (TMEM48) is a protein that is expressed in various tissues throughout the body, including the brain, heart, and kidneys. It is a member of the transmembrane protein family, which means that it spans the cell membrane and functions as a protein that interacts with other proteins in the same or other cells.

NDC1 has been identified as a potential drug target or biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Its unique structure and various functions have made it an attractive target for researchers to study and develop new treatments.

One of the key reasons for the interest in NDC1 is its role in the regulation of cellular processes that are important for human health and disease. For example, NDC1 has been shown to be involved in the regulation of cell death, stem cell maintenance, and inflammation.

In addition, NDC1 has also been shown to play a role in the development and progression of various diseases, including cancer. Studies have shown that high levels of NDC1 are associated with the development of cancer, and that inhibiting its activity may be a useful strategy for cancer treatment.

Another potential use of NDC1 as a drug target is its role in the regulation of the immune system. NDC1 has been shown to interact with immune cells and play a role in the development of immune tolerance. This suggests that NDC1 may be a useful target for drugs that are designed to enhance or inhibit the immune system.

The structure of NDC1 also makes it an attractive target for small molecule inhibitors. Studies have shown that various small molecules have been shown to interact with NDC1 and inhibit its activity. These compounds have the potential to be used as drugs for a variety of conditions, including cancer, neurodegenerative diseases, and autoimmune disorders.

In conclusion, NDC1 is a protein that has significant potential as a drug target or biomarker. Its unique structure and various functions make it an attractive target for researchers to study and develop new treatments for a variety of conditions. Further research is needed to fully understand the role of NDC1 in human health and disease, and to develop effective treatments based on its properties.

Protein Name: NDC1 Transmembrane Nucleoporin

Functions: Component of the nuclear pore complex (NPC), which plays a key role in de novo assembly and insertion of NPC in the nuclear envelope. Required for NPC and nuclear envelope assembly, possibly by forming a link between the nuclear envelope membrane and soluble nucleoporins, thereby anchoring the NPC in the membrane

The "NDC1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about NDC1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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