Target Name: NDUFA1
NCBI ID: G4694
Review Report on NDUFA1 Target / Biomarker Content of Review Report on NDUFA1 Target / Biomarker
NDUFA1
Other Name(s): NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 | MWFE | ZNF183 | CI-MWF | complex I MWFE subunit | Complex I-MWFE | NADH:ubiquinone oxidoreductase subunit A1 | type I dehydrogenase | MWFEE | CI-MWFE | NDUA1_HUMAN | Type I dehydrogenase | NADH oxidoreductase subunit MWFE | MC1DN12 | NADH:ubiquinone oxidoreductase (complex 1) | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa | NADH-ubiquinone oxidoreductase MWFE subunit | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1 (7.5kD, MWFE) | Complex I MWFE subunit

NDUFA1: Key Subunit of The NADH Dehydrogenase Enzyme Complex

NDUFA1, or NADH dehydrogenase alpha subunit 1, is a protein that plays a critical role in the metabolism of nitrogen compounds, such as nitrates and ammonia. It is a subunit of the NADH dehydrogenase enzyme complex, which is responsible for converting NAD+, a crucial coenzyme found in red blood cells, to NADH, a less reactive molecule that can be used to generate ATP energy.

The NADH dehydrogenase enzyme complex is a complex protein that consists of multiple subunits, including NDUFA1, which is a key subunit that is involved in the alpha subunit. NDUFA1 is a 16-kDa protein that consists of 155 amino acids. It has a molecular weight of 19,917.44 daltons and a calculated pI of 2.85.

The NADH dehydrogenase enzyme complex is a critical enzyme in the metabolism of nitrogen compounds, such as nitrates and ammonia. Nitrogen is a crucial compound for life, and it is involved in many important cellular processes, including the production of proteins, DNA, and RNA , as well as the regulation of gene expression. NADH is a less reactive molecule that can be used to generate ATP energy, but it is a critical coenzyme for many cellular processes, including the production of ATP from ADP.

NDUFA1 is a key subunit of the NADH dehydrogenase enzyme complex because it is involved in the alpha subunit, which is responsible for the conversion of NAD+ to NADH. The alpha subunit is the active site of the enzyme, where the substrate, NAD+, is converted to NADH. NDUFA1 is the subunit that is responsible for the structural stability of the alpha subunit.

The NADH dehydrogenase enzyme complex is a complex protein that consists of multiple subunits, including NDUFA1.

NDUFA1 is a 16-kDa protein that consists of 155 amino acids. It has a molecular weight of 19,917.44 daltons and a calculated pI of 2.85. NDUFA1 has a single alpha helix and a single beta sheet. The alpha sheet has three beta strands and a alpha helix, while the beta sheet has one beta strand and a beta sheet.

NDUFA1 is involved in the NADH dehydrogenase enzyme complex because it is a key subunit of the alpha subunit. The alpha subunit is the active site of the enzyme, where the substrate, NAD+, is converted to NADH. NDUFA1 is the subunit that is responsible for the structural stability of the alpha subunit.

The NADH dehydrogenase enzyme complex is a critical enzyme in the metabolism of nitrogen compounds, such as nitrates and ammonia. Nitrogen is a crucial compound for life, and it is involved in many important cellular processes, including the production of proteins, DNA, and RNA , as well as the regulation of gene expression. NADH is a less reactive molecule that can be used to generate ATP energy, but it is a critical coenzyme for many cellular processes, including the production of ATP from ADP.

NDUFA1 is a key subunit of the NADH dehydrogenase enzyme complex because it is involved in the alpha subunit, which is responsible for the conversion of NAD+ to NADH. The alpha subunit is the active site of the enzyme, where the substrate, NAD+, is converted to NADH. NDUFA1 is the subunit that is responsible for the structural stability of the alpha subunit.

The NADH dehydrogenase enzyme complex is a critical enzyme in the metabolism of nitrogen compounds, such as nitrates and ammonia. Nitrogen is a crucial compound for life, and it is involved in many important cellular processes, including the production of proteins, DNA, and RNA , as well as the regulation of gene expression. NADH is a less reactive molecule that can be used to generate ATP energy, but it is a critical coenzyme for many cellular processes, including the production of ATP from ADP.

In conclusion, NDUFA1 is a key subunit of the NADH dehydrogenase enzyme complex because it is involved in the alpha subunit, which is responsible for the conversion of NAD+ to NADH. The alpha subunit is the active site of the enzyme, where the substrate, NAD+ , is converted to NADH. NDUFA1 is the subunit that is responsible for the structural stability of the alpha subunit. Further research is needed to understand the full role of NDUFA1 in the NADH dehydrogenase enzyme complex and its potential as a drug target or biomarker.

Protein Name: NADH:ubiquinone Oxidoreductase Subunit A1

Functions: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

The "NDUFA1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about NDUFA1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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NDUFA10 | NDUFA11 | NDUFA12 | NDUFA13 | NDUFA2 | NDUFA3 | NDUFA3P3 | NDUFA4 | NDUFA4L2 | NDUFA5 | NDUFA5P11 | NDUFA6 | NDUFA6-DT | NDUFA7 | NDUFA8 | NDUFA9 | NDUFAB1 | NDUFAF1 | NDUFAF2 | NDUFAF3 | NDUFAF4 | NDUFAF4P1 | NDUFAF5 | NDUFAF6 | NDUFAF7 | NDUFAF8 | NDUFB1 | NDUFB10 | NDUFB11 | NDUFB2 | NDUFB2-AS1 | NDUFB3 | NDUFB4 | NDUFB5 | NDUFB6 | NDUFB7 | NDUFB8 | NDUFB9 | NDUFC1 | NDUFC2 | NDUFC2-KCTD14 | NDUFS1 | NDUFS2 | NDUFS3 | NDUFS4 | NDUFS5 | NDUFS6 | NDUFS7 | NDUFS8 | NDUFV1 | NDUFV2 | NDUFV2P1 | NDUFV3 | NEAT1 | NEB | NEBL | NECAB1 | NECAB2 | NECAB3 | NECAP1 | NECAP2 | NECTIN1 | NECTIN2 | NECTIN3 | NECTIN3-AS1 | NECTIN4 | NEDD1 | NEDD4 | NEDD4L | NEDD8 | NEDD8-activating enzyme E1 | NEDD8-MDP1 | NEDD9 | NEFH | NEFHP1 | NEFL | NEFM | NEGR1 | NEGR1-IT1 | NEIL1 | NEIL2 | NEIL3 | NEK1 | NEK10 | NEK11 | NEK2 | NEK2-DT | NEK3 | NEK4 | NEK5 | NEK6 | NEK7 | NEK8 | NEK9 | NELF Complex | NELFA | NELFB | NELFCD | NELFE | NELL1