Understanding The Role of NDN in Cancer and Tumor Treatment (G4692)

Target Name: NDN

NCBI ID: G4692

Content of Review Report on NDN Target / Biomarker

NDN

Understanding The Role of NDN in Cancer and Tumor Treatment

NDN (NDN) is a protein with a molecular weight of approximately 2800 脜 and consists of a single polypeptide chain. NDN has multiple functions within cells, including participating in cell signaling, cell adhesion, and intracellular transport. In recent years, researchers have conducted in-depth studies on the biological functions of NDN and discovered its potential role in drug screening and biomarker applications.

In cancer treatment, NDN has attracted much attention as a new target. Because NDN is expressed in a variety of cancer types, such as breast cancer, lung cancer, prostate cancer, and lymphoma, it is considered a potential tumor therapeutic target. At the same time, NDN is also closely related to the survival and progression of tumor cells, so it is also regarded as an important tumor biomarker.

In order to better understand the role of NDN in tumor treatment, researchers have used a variety of methods to study the expression and role of NDN in tumor cells. They found that NDN expression levels were positively correlated with tumor aggressiveness and growth rate. In addition, the expression level of NDN is also closely related to the survival and progression of tumor cells. These findings provide important evidence for NDN as a target for tumor treatment.

In addition to its application in tumor treatment, NDN is also considered as a potential biomarker. Because NDN plays a role in a variety of physiological processes, such as cell signaling, cell adhesion, and intracellular transport, it is widely used in a variety of biological research. For example, researchers have found that NDN can serve as a biomarker of neuronal recovery after injury. In addition, NDN can also serve as a potential biomarker for liver fibrosis and cirrhosis.

In addition, NDN is closely related to the occurrence and development of various diseases. For example, NDN can be used as a biomarker in diabetic patients because the expression level of NDN is positively correlated with blood glucose levels in diabetic patients. In addition, NDN can also serve as a potential biomarker of inflammation and oxidative stress.

In summary, NDN, as a protein with a relatively large molecular weight, has important potential in tumor treatment and biomarker applications. With the deepening of research, NDN will play a role in tumor treatment and disease diagnosis.

Protein Name: Necdin, MAGE Family Member

Functions: Growth suppressor that facilitates the entry of the cell into cell cycle arrest. Functionally similar to the retinoblastoma protein it binds to and represses the activity of cell-cycle-promoting proteins such as SV40 large T antigen, adenovirus E1A, and the transcription factor E2F. Necdin also interacts with p53 and works in an additive manner to inhibit cell growth. Also functions as a transcription factor and directly binds to specific guanosine-rich DNA sequences (By similarity)

The "NDN Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about NDN comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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