The NDUFA10 Subunit: A Potential Drug Target and Biomarker for Diseases

Target Name: NDUFA10

NCBI ID: G4705

NDUFA10

The NDUFA10 Subunit: A Potential Drug Target and Biomarker for Diseases

The NDUFA10 subunit is a protein that is expressed in various tissues throughout the body. It is a key component of the complex I 42kDa, which is a subunit of the electron transport chain in the mitochondria. TheNDUFA10 subunit has been identified as a potential drug target and a biomarker for various diseases, including cancer, neurodegenerative diseases, and respiratory disorders.

TheNDUFA10 subunit is composed of four subunits, which are located in different regions of the protein. The N-terminus of the subunit contains a unique domain that is known as the N-terminal alpha-helicase domain. This domain is responsible for the subunit's ability to interact with other proteins and for its role in the electron transport chain. The alpha-helicase domain is composed of a unique farnesylated cysteine 鈥嬧?媟esidue, which is important for the subunit's stability and function.

The middle region of the subunit contains a domain that is known as the alpha-helical domain. This domain is responsible for the subunit's alpha-helicase activity and for its role in the electron transport chain. The alpha-helical region is composed of a series of parallel alpha-helices that are responsible for the subunit's stability and function.

The C-terminus of the subunit contains a unique domain that is known as the C-terminal dextranugal domain. This domain is responsible for the subunit's ability to interact with other proteins and for its role in the electron transport chain. The dextranugal domain is composed of a unique amino acid sequence that is important for the subunit's stability and function.

TheNDUFA10 subunit has been shown to play a role in a variety of biological processes, including the electron transport chain, metabolism, and disease. For example, studies have shown that theNDUFA10 subunit is involved in the electron transport chain and is a key component of the complex I 42kDa. This suggests that the subunit may be a useful target for drugs that are designed to modulate the electron transport chain and to treat a variety of diseases.

In addition to its role in the electron transport chain, theNDUFA10 subunit has also been shown to play a role in a variety of diseases. For example, studies have shown that the subunit is involved in the development and progression of neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease. This suggests that the subunit may be a useful biomarker for these diseases and that it may be a potential drug target.

TheNDUFA10 subunit has also been shown to be involved in the regulation of cellular metabolism. For example, studies have shown that the subunit is involved in the regulation of cellular energy metabolism and that it plays a role in the production of reactive oxygen species (ROS) . This suggests that the subunit may be a useful target for drugs that are designed to modulate cellular metabolism and to treat a variety of diseases.

In conclusion, theNDUFA10 subunit is a protein that is expressed in various tissues throughout the body and is involved in a variety of biological processes, including the electron transport chain and disease. As a result, it has been identified as a potential drug target and biomarker for a variety of diseases, including cancer, neurodegenerative diseases, and respiratory disorders. Further research is needed to fully understand the role of the NDUFA10 subunit in these diseases and to develop effective treatments.

Protein Name: NADH:ubiquinone Oxidoreductase Subunit A10

Functions: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

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•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
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•   the target screening and validation;
•   expression level;
•   disease relevance;
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•   related combination drugs;
•   pharmacochemistry experiments;
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•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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