Regulation of Gene Expression By GTF2F1 (G2962)

Target Name: GTF2F1

NCBI ID: G2962

GTF2F1

Regulation of Gene Expression By GTF2F1

General Transcription Factor IIF (GTF2F1), also known as GFF123, is a subunit of the GTF2F complex that plays a crucial role in the regulation of gene expression. GTF2F1 is composed of two distinct subunits, GTF2F1伪 and GTF2F1尾, which are responsible for distinct functions in gene regulation. The GTF2F1伪 subunit is predominantly expressed in the brain, while the GTF2F1尾 subunit is predominantly expressed in the liver and other organs.

The GTF2F1伪 subunit is composed of 116 amino acid residues and has a calculated molecular weight of 19.1 kDa. It contains a N-terminal domain that is similar to other transcription factors, including DNA-binding domains. The N-terminal domain is responsible for interacting with DNA and for regulating the expression of target genes.

The GTF2F1尾 subunit is composed of 194 amino acid residues and has a calculated molecular weight of 37.4 kDa. It contains a N-terminal domain that is similar to other transcription factors, including DNA-binding domains. The N-terminal domain is responsible for interacting with DNA and for regulating the expression of target genes.

Both subunits of GTF2F1 contain a unique N-terminal domain that is responsible for their unique functions in gene regulation. The N-terminal domain of GTF2F1伪 contains a nucleotide-binding domain (NBD), which is responsible for interacting with DNA and for regulating the expression of target genes. The N-terminal domain of GTF2F1尾 contains a leucine-rich repeat (LRR) domain, which is responsible for interacting with DNA and for regulating the expression of target genes.

The GTF2F1伪 subunit has been shown to play a role in the regulation of various genes, including neurotransmitter synthesis and release, as well as cell adhesion. For example, GTF2F1伪 has been shown to regulate the expression of genes involved in the synthesis and release of neurotransmitters, such as dopamine and serotonin. It has also been shown to play a role in the regulation of cell adhesion, including the regulation of tight junctions and cadherins.

The GTF2F1尾 subunit has also been shown to play a role in the regulation of various genes, including gene expression involved in cell adhesion, as well as the regulation of cell survival. For example, GTF2F1尾 has been shown to regulate the expression of genes involved in cell adhesion, including the regulation of cadherins and tight junctions. It has also been shown to play a role in the regulation of cell survival, including the regulation of cell apoptosis.

Despite the importance of GTF2F1 in gene regulation, little is known about its specific mechanism of action. However, several studies have shown that GTF2F1伪 and GTF2F1尾 are involved in the regulation of gene expression in various organisms, including mammals.

In conclusion, GTF2F1 is a subunit of the GTF2F complex that plays a crucial role in the regulation of gene expression. The N-terminal domain of GTF2F1伪 and GTF2F1尾 is responsible for their unique functions in gene regulation. While the specific mechanism of action of GTF2F1 is not well understood, its involvement in the regulation of gene expression is clear. As a potential drug target or biomarker, GTF2F1 may be a useful target for the study of various diseases, including neurodegenerative disorders.

Protein Name: General Transcription Factor IIF Subunit 1

Functions: TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation

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