Target Name: ATOSA
NCBI ID: G56204
Review Report on ATOSA Target / Biomarker Content of Review Report on ATOSA Target / Biomarker
ATOSA
Other Name(s): family with sequence similarity 214 member A | Protein FAM214A (isoform 1) | Atos homolog A, transcript variant 1 | atos homolog A | KIAA1370 | F214A_HUMAN | Hypothetical protein LOC56204 | ATOSA variant 1 | FLJ10980 | MGC126494 | Protein FAM214A | FAM214A

ATOSA: A Potential Drug Target and Biomarker for Family with Sequence Similarity 214

ATOSA is a family of proteins that share a sequence similarity of 214 base pairs between its amino acid residues. These proteins are known as AT-domain containing proteins and are involved in various cellular processes, including cell signaling, DNA replication, and metabolism. The discovery of ATOSA as a potential drug target and biomarker has significant implications for the development of new therapeutic strategies for various diseases.

Molecular Structure and Function

ATOSA is a protein that can be expressed in a variety of organisms, including humans. The protein has a molecular structure that consists of an N-terminal alpha-helices region, a sequence of 214 amino acids, and a C-terminal T-loop region. The N-terminal and C-terminal regions contain putative nuclear localization domains (NLDs) and CLDs, respectively, which are involved in protein-protein interactions and may play a role in the protein's stability and localization to the nuclear envelope.

The ATOSA protein is involved in various cellular processes, including the regulation of DNA replication, cell signaling, and metabolism. One of the well-established functions of ATOSA is its role in the regulation of DNA replication. ATOSA is a component of the complex DNA replication machinery, which is responsible for copying the genetic information from one generation to the next.

ATOSA has been shown to play a critical role in the regulation of DNA replication in various organisms, including bacteria and yeast. In bacteria, ATOSA is involved in the regulation of DNA replication by preventing the access of the DNA replication machinery to the replication factors required for DNA replication. In yeast, ATOSA is involved in the regulation of DNA replication by controlling the assembly and disassembly of the replication factors.

In addition to its role in DNA replication, ATOSA is also involved in the regulation of cell signaling. The ATOSA gene has been shown to be involved in the regulation of various cellular signaling pathways, including the regulation of cell growth, cell differentiation, and cell survival.

ATOSA is also involved in the regulation of metabolism, including energy metabolism and metabolism of nutrients. In various organisms, ATOSA is involved in the regulation of energy metabolism, including the metabolism of glucose and fatty acids.

Discovery as a Drug Target

The discovery of ATOSA as a potential drug target has significant implications for the development of new therapeutic strategies for various diseases. ATOSA has been shown to play a critical role in the regulation of DNA replication, cell signaling, and metabolism, making it an attractive target for small molecules that can modulate these processes.

Various studies have identified potential small molecules that can interact with ATOSA and modulate its activity. These small molecules include inhibitors of DNA replication, inhibitors of cell signaling, and inhibitors of metabolism. These small molecules have been shown to have a wide range of effects on various cellular processes, including the regulation of cell growth, cell differentiation, and cell survival.

In addition to its potential as a drug target, ATOSA also has the potential as a biomarker for the diagnosis and monitoring of various diseases. The regulation of DNA replication is a critical process that is affected by a wide range of diseases, including cancer, cardiovascular disease, and neurodegenerative diseases.

Conclusion

ATOSA is a family of proteins that share a sequence similarity of 214 base pairs between its amino acid residues. These proteins are involved in various cellular processes, including cell signaling, DNA replication, and metabolism. The discovery of ATOSA as a potential drug target and biomarker has significant implications for the development of new therapeutic strategies for various diseases. Further research is needed to fully understand the

Protein Name: Atos Homolog A

Functions: Transcription regulator that syncronizes transcriptional and translational programs to promote macrophage invasion of tissues

The "ATOSA Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ATOSA comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

ATOSB | ATOX1 | ATOX1-AS1 | ATP Synthase, H+ Transporting, Mitochondrial F0 complex | ATP synthase, H+ transporting, mitochondrial F1 complex | ATP-Binding Cassette (ABC) Transporter | ATP-dependent 6-phosphofructokinase | ATP10A | ATP10B | ATP10D | ATP11A | ATP11A-AS1 | ATP11AUN | ATP11B | ATP11C | ATP12A | ATP13A1 | ATP13A2 | ATP13A3 | ATP13A3-DT | ATP13A4 | ATP13A5 | ATP13A5-AS1 | ATP1A1 | ATP1A1-AS1 | ATP1A2 | ATP1A3 | ATP1A4 | ATP1B1 | ATP1B2 | ATP1B3 | ATP1B4 | ATP23 | ATP2A1 | ATP2A1-AS1 | ATP2A2 | ATP2A3 | ATP2B1 | ATP2B1-AS1 | ATP2B2 | ATP2B3 | ATP2B4 | ATP2C1 | ATP2C2 | ATP4A | ATP4B | ATP5F1A | ATP5F1B | ATP5F1C | ATP5F1D | ATP5F1E | ATP5F1EP2 | ATP5IF1 | ATP5MC1 | ATP5MC1P3 | ATP5MC2 | ATP5MC3 | ATP5ME | ATP5MF | ATP5MG | ATP5MGL | ATP5MJ | ATP5MK | ATP5PB | ATP5PBP5 | ATP5PD | ATP5PDP3 | ATP5PF | ATP5PO | ATP6 | ATP6AP1 | ATP6AP1-DT | ATP6AP1L | ATP6AP2 | ATP6V0A1 | ATP6V0A2 | ATP6V0A4 | ATP6V0B | ATP6V0C | ATP6V0CP1 | ATP6V0CP3 | ATP6V0D1 | ATP6V0D1-DT | ATP6V0D2 | ATP6V0E1 | ATP6V0E1P1 | ATP6V0E2 | ATP6V0E2-AS1 | ATP6V1A | ATP6V1B1 | ATP6V1B2 | ATP6V1C1 | ATP6V1C2 | ATP6V1D | ATP6V1E1 | ATP6V1E2 | ATP6V1F | ATP6V1FNB | ATP6V1G1 | ATP6V1G1P1