Target Name: ATP11B
NCBI ID: G23200
Review Report on ATP11B Target / Biomarker Content of Review Report on ATP11B Target / Biomarker
ATP11B
Other Name(s): ATPase, class VI, type 11B | ATPIF | ATPase class VI type 11B | Probable phospholipid-transporting ATPase IF | P4-ATPase flippase complex alpha subunit ATP11B | probable phospholipid-transporting ATPase IF | ATPase IR | truncated ATPase 11B protein | AT11B_HUMAN | DKFZP434N1615 | ATPIR | Phospholipid-transporting ATPase IF | Potential phospholipid-transporting ATPase IF | MGC46576 | ATPase phospholipid transporting 11B (putative) | KIAA0956 | DKFZP434J238

ATPase: Key Enzyme for ATP Production

ATPase, class VI, type 11B is a protein that plays a crucial role in the production of ATP (adenosine triphosphate), which is a key energy source for the cell. It is an essential enzyme that catalyzes the transfer of a phosphate group from the ATP synthase to ADP, resulting in the formation of ATP. class VI enzymes are a subclass of ATPases that catalyze the production of ATP from ADP and Pi (phosphate inositol). type 11B is one of the subclasses of class VI enzymes.

ATP is a high-energy molecule that is involved in various cellular processes, including muscle contractions, neural transmission, and chromatin remodeling. It is a large molecule that contains an A-P ring, a B-P ring, and a C-P ring. The A-P ring consists of a carbon atom, an oxygen atom, and a phosphate group, while the B-P ring consists of a carbon atom, an oxygen atom, and a phosphate group. The C-P ring consists of a carbon atom, an oxygen atom, and a phosphate group.

In the process of ATP production, the ATPase enzyme uses the energy from the Pi to activate the phosphate group on the A-P ring, which then transfers a phosphate group to the B-P ring. This process results in the formation of ATP. ATPase is a critical enzyme that is involved in the production of ATP from ADP and Pi.

ATPase is a protein that is expressed in most cell types and is involved in various cellular processes. It is a nucleotide-binding protein and is composed of a single polypeptide chain. It has a molecular weight of 183 kDa and a calculated pI of 6.9. ATPase is a monomer and has a single transmembrane region.

ATPase is a potent drug target and has been shown to be involved in various diseases. For example, ATPase has been shown to be involved in the development of cancer, neurodegenerative diseases, and cardiovascular diseases. It is also a potential biomarker for various diseases.

In conclusion, ATPase, class VI, type 11B is a protein that plays a crucial role in the production of ATP, which is an essential energy source for the cell. It is an essential enzyme that catalyzes the transfer of a phosphate group from the ATP synthase to ADP, resulting in the formation of ATP. class VI enzymes are a subclass of ATPases that catalyze the production of ATP from ADP and Pi. type 11B is one of the subclasses of class VI enzymes. It is a critical enzyme that is involved in various cellular processes and is a potential drug target and biomarker for various diseases.

Protein Name: ATPase Phospholipid Transporting 11B (putative)

Functions: Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids, phosphatidylserines (PS) and phosphatidylethanolamines (PE), from the outer to the inner leaflet of intracellular membranes (PubMed:30018401). May contribute to the maintenance of membrane lipid asymmetry in endosome compartment (PubMed:30018401)

The "ATP11B Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ATP11B comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

ATP11C | ATP12A | ATP13A1 | ATP13A2 | ATP13A3 | ATP13A3-DT | ATP13A4 | ATP13A5 | ATP13A5-AS1 | ATP1A1 | ATP1A1-AS1 | ATP1A2 | ATP1A3 | ATP1A4 | ATP1B1 | ATP1B2 | ATP1B3 | ATP1B4 | ATP23 | ATP2A1 | ATP2A1-AS1 | ATP2A2 | ATP2A3 | ATP2B1 | ATP2B1-AS1 | ATP2B2 | ATP2B3 | ATP2B4 | ATP2C1 | ATP2C2 | ATP4A | ATP4B | ATP5F1A | ATP5F1B | ATP5F1C | ATP5F1D | ATP5F1E | ATP5F1EP2 | ATP5IF1 | ATP5MC1 | ATP5MC1P3 | ATP5MC2 | ATP5MC3 | ATP5ME | ATP5MF | ATP5MG | ATP5MGL | ATP5MJ | ATP5MK | ATP5PB | ATP5PBP5 | ATP5PD | ATP5PDP3 | ATP5PF | ATP5PO | ATP6 | ATP6AP1 | ATP6AP1-DT | ATP6AP1L | ATP6AP2 | ATP6V0A1 | ATP6V0A2 | ATP6V0A4 | ATP6V0B | ATP6V0C | ATP6V0CP1 | ATP6V0CP3 | ATP6V0D1 | ATP6V0D1-DT | ATP6V0D2 | ATP6V0E1 | ATP6V0E1P1 | ATP6V0E2 | ATP6V0E2-AS1 | ATP6V1A | ATP6V1B1 | ATP6V1B2 | ATP6V1C1 | ATP6V1C2 | ATP6V1D | ATP6V1E1 | ATP6V1E2 | ATP6V1F | ATP6V1FNB | ATP6V1G1 | ATP6V1G1P1 | ATP6V1G2 | ATP6V1G2-DDX39B | ATP6V1G3 | ATP6V1H | ATP7A | ATP7B | ATP8 | ATP8A1 | ATP8A2 | ATP8B1 | ATP8B1-AS1 | ATP8B2 | ATP8B3 | ATP8B4