ACADSB: Key Enzyme in Fatty Acid Metabolism (G36)

Target Name: ACADSB

NCBI ID: G36

ACADSB

ACADSB: Key Enzyme in Fatty Acid Metabolism

2-Methylbutyryl-CoA (BMB) dehydrogenase (ACADSB) is a protein that is involved in the metabolism of fatty acids in the body. It is a key enzyme in the citric acid cycle, also known as the Krebs cycle or tricarboxylic acid (TCA) cycle, which is a central metabolic pathway that produces energy from food.

ACADSB is a 24-kDa protein that is expressed in various tissues throughout the body, including muscle, heart, liver, and brain. It is primarily localized to the mitochondria, where it is involved in the final step of the TCA cycle, the production of carbon dioxide and water as a byproduct.

ACADSB functions as a critical enzyme in the TCA cycle by catalyzing the conversion of 2-methylbutyryl-CoA (BMB) to butyrate. BMB is a fatty acid that is derived from the amino acids leucine and is found in high concentrations in muscle and other tissues. The production of BMB from Leucine is a critical step in the TCA cycle and is critical for the production of energy from food.

ACADSB is a protein that is expressed in various tissues throughout the body and is primarily localized to the mitochondria. It is involved in the final step of the TCA cycle, the production of carbon dioxide and water as a byproduct. (Image Credit: Science/Google)

ACADSB is a protein that is involved in the production of energy from the food we eat. It is a key enzyme in the TCA cycle and is primarily localized to the mitochondria, where it is involved in the final step of the cycle, the production of carbon dioxide and water as a byproduct.

One of the key functions of ACADSB is its role in the production of butyrate, a compound that is derived from the amino acids leucine and is used as a source of energy in the body. Butyrate is produced by the body and is found in high concentrations in muscle and other tissues.

ACADSB is also involved in the regulation of the levels of carbon dioxide in the body. It is a critical enzyme in the TCA cycle and is involved in the production of carbon dioxide and water as a byproduct. This process is essential for the regulation of the carbon dioxide levels in the body, which are important for the production of energy by the body.

ACADSB is also involved in the regulation of the levels of butyrate in the body. It is a critical enzyme in the TCA cycle and is involved in the production of butyrate from the amino acids leucine. This process is essential for the maintenance of the body's energy levels.

In addition to its role in the TCA cycle, ACADSB is also involved in the regulation of various cellular processes in the body. It is a critical enzyme in the citric acid cycle, which is a central metabolic pathway that produces energy from food. It is also involved in the regulation of the levels of oxygen in the body, which is important for the production of energy by the body.

ACADSB is a protein that is involved in the production of energy from the food we eat. It is a key enzyme in the TCA cycle and is primarily localized to the mitochondria, where it is involved in the final step of the cycle, the production of carbon dioxide and water as a byproduct. (Image Credit: Science/Google)

ACADSB is a protein that is involved in the production of carbon dioxide and water as a byproduct from the food we eat. It is a key enzyme in the TCA cycle and is primarily localized to the mitochondria, where it is involved in the final step of the cycle, the production of carbon dioxide and water as a byproduct.

In conclusion, ACADSB is a protein that is involved in

Protein Name: Acyl-CoA Dehydrogenase Short/branched Chain

Functions: Short and branched chain specific acyl-CoA dehydrogenase that catalyzes the removal of one hydrogen from C-2 and C-3 of the fatty acyl-CoA thioester, resulting in the formation of trans-2-enoyl-CoA (PubMed:7698750, PubMed:11013134, PubMed:21430231, PubMed:10832746). Among the different mitochondrial acyl-CoA dehydrogenases, acts specifically on short and branched chain acyl-CoA derivatives such as (S)-2-methylbutyryl-CoA as well as short straight chain acyl-CoAs such as butyryl-CoA (PubMed:7698750, PubMed:11013134, PubMed:21430231, PubMed:10832746). Plays an important role in the metabolism of L-isoleucine by catalyzing the dehydrogenation of 2-methylbutyryl-CoA, one of the steps of the L-isoleucine catabolic pathway (PubMed:11013134, PubMed:10832746). Can also act on valproyl-CoA, a metabolite of valproic acid, an antiepileptic drug (PubMed:8660691)

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