KRTAP10-7: A Potential Drug Target and Biomarker (G386675)

Target Name: KRTAP10-7

NCBI ID: G386675

KRTAP10-7

KRTAP10-7: A Potential Drug Target and Biomarker

Keratin-associated protein 10-7 (KRTAP10-7) is a protein that has been identified as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Its unique structure and subcellular localization make it an attractive target for small molecule inhibitors. In this article, we will discuss the biology of KRTAP10-7, its potential drug targets, and its potential as a biomarker for disease.

Structure and Localization

KRTAP10-7 is a 120-kDa protein that is expressed in most tissues of the body. It is highly conserved, with a calculated pI of 6.9 and a predicted localization in the cytoplasm. KRTAP10-7 has a unique structure, with a molecular weight of 19.1 kDa and a calculated molecular density of 40%. It has four known functions, including actin cytoskeleton organization, cytoplasmic organization of organelles, and modulation of cell adhesion and migration.

KRTAP10-7 is a cytoplasmic protein that is involved in the cytoskeleton organization and regulation of actin filaments. It is a component of the actin cytoskeleton and has been shown to interact with several other cytoskeleton proteins, including actinin and microtubules. Its localization in the cytoplasm suggests that it plays a role in the regulation of cytoplasmic organization and the distribution of organelles.

Potential Drug Targets

KRTAP10-7 has several potential drug targets, including G protein-coupled receptors (GPCRs), tyrosine kinases, and integrins. GPCRs are a family of transmembrane proteins that play a role in cellular signaling, including sensory perception and neurotransmission. Tyrosine kinases are a family of enzymes that are involved in cell signaling, including the regulation of cell growth and differentiation. Integrins are a family of proteins that are involved in cell adhesion and migration.

In addition to these protein targets, KRTAP10-7 has also been shown to interact with several small molecules, including inhibitors of tyrosine kinase activity and GPCRs. This suggests that it may be an attractive target for small molecule inhibitors.

Potential Biomarker

KRTAP10-7 has been shown to play a role in the regulation of cell adhesion and migration, which makes it an attractive biomarker for various diseases. Its expression has been shown to be regulated by several factors, including cell type, signaling pathways, and small molecules.

In addition to its role in cell adhesion and migration, KRTAP10-7 has also been shown to play a role in the regulation of cell proliferation and apoptosis. Its expression has been shown to be regulated by several factors, including growth factors, inhibitors of apoptosis, and stress signaling pathways.

Conclusion

In conclusion, KRTAP10-7 is a protein that has unique structure and localization, making it an attractive target for small molecule inhibitors. Its potential drug targets include GPCRs, tyrosine kinases, and integrins, as well as several small molecules that have been shown to interact with its cytoskeleton organization and regulation of cell adhesion and migration. Its potential as a biomarker for various diseases makes it an important molecule for future research. Further studies are needed to fully understand its role in cellular signaling and its potential as a drug target.

Protein Name: Keratin Associated Protein 10-7

Functions: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins

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The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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