Target Name: KRTAP19-3
NCBI ID: G337970
Review Report on KRTAP19-3 Target / Biomarker Content of Review Report on KRTAP19-3 Target / Biomarker
KRTAP19-3
Other Name(s): KR193_HUMAN | GTHRP | Keratin-associated protein 19-3 | glycine/tyrosine-rich protein | GTRHP | Keratin associated protein 19-3 | KAP19.3 | keratin associated protein 19-3 | Glycine/tyrosine-rich protein

Structure and Function of KRTAP19-3: A Protein of Interest

KRTAP19-3 (KR193_HUMAN) is a protein that is expressed in various tissues of the human body, including the brain, heart, liver, and pancreas. It is a member of the KRTAS family, which includes proteins that are involved in various cellular processes, including cell signaling, DNA replication, and protein synthesis.

KRTAP19-3 is unique because of its structure and function. It is a transmembrane protein, which means that it spans the cell membrane and is involved in various membrane-based signaling pathways. Additionally, KRTAP19-3 is a protein that is involved in the regulation of gene expression, which is a critical process that allows cells to respond to various stimuli and ensure that they maintain a stable internal environment.

KRTAP19-3 is also worth noting because of its potential as a drug target. Its unique structure and function make it an attractive target for researchers to study and potentially develop into a new drug. Additionally, its involvement in cellular signaling pathways makes it a potential target for drugs that are designed to modulate cellular signaling pathways, such as those that are used to treat a variety of diseases, including cancer, neurodegenerative diseases, and cardiovascular diseases.

One of the challenges in studying KRTAP19-3 is its expression. While it is widely expressed in various tissues of the human body, its expression is not consistent across all cell types and conditions. This makes it difficult to study its effects and potential as a drug target. Additionally, the structure and function of KRTAP19-3 are not well understood, which can make it difficult to design and optimize potential drugs that target its activity.

Despite these challenges, research into KRTAP19-3 is ongoing. Researchers are using various techniques, including cell-based assays, biochemical assays, and mass spectrometry, to study its expression and function. They are also using computational tools, such as molecular docking and molecular dynamics simulations, to gain a better understanding of its structure and behavior.

In addition to its potential as a drug target, KRTAP19-3 is also of interest to researchers because of its potential role in the development of certain diseases. For example, KRTAP19-3 has been shown to be involved in the development of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. Additionally, it has also been associated with the development of certain cardiovascular diseases, such as heart failure and myocardial infarction.

Overall, KRTAP19-3 is a protein that is of interest to researchers due to its unique structure and function. While its expression and function are not well understood, research into its potential as a drug target and its potential role in the development of certain diseases is ongoing. As research continues, it is likely that new insights into its structure and function will emerge, and new drugs or therapies may be developed that target its activity.

Protein Name: Keratin Associated Protein 19-3

Functions: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins

The "KRTAP19-3 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about KRTAP19-3 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

KRTAP19-4 | KRTAP19-5 | KRTAP19-6 | KRTAP19-7 | KRTAP19-8 | KRTAP2-1 | KRTAP2-2 | KRTAP2-3 | KRTAP2-4 | KRTAP20-1 | KRTAP20-2 | KRTAP20-3 | KRTAP20-4 | KRTAP21-1 | KRTAP21-2 | KRTAP21-3 | KRTAP22-1 | KRTAP22-2 | KRTAP23-1 | KRTAP25-1 | KRTAP26-1 | KRTAP27-1 | KRTAP29-1 | KRTAP3-1 | KRTAP3-2 | KRTAP3-3 | KRTAP4-1 | KRTAP4-11 | KRTAP4-12 | KRTAP4-2 | KRTAP4-3 | KRTAP4-4 | KRTAP4-5 | KRTAP4-6 | KRTAP4-7 | KRTAP4-8 | KRTAP4-9 | KRTAP5-1 | KRTAP5-10 | KRTAP5-11 | KRTAP5-14P | KRTAP5-2 | KRTAP5-3 | KRTAP5-4 | KRTAP5-5 | KRTAP5-7 | KRTAP5-8 | KRTAP5-9 | KRTAP5-AS1 | KRTAP6-1 | KRTAP6-2 | KRTAP6-3 | KRTAP7-1 | KRTAP8-1 | KRTAP9-1 | KRTAP9-2 | KRTAP9-3 | KRTAP9-4 | KRTAP9-6 | KRTAP9-7 | KRTAP9-8 | KRTAP9-9 | KRTCAP2 | KRTCAP3 | KRTDAP | KSR1 | KSR1P1 | KSR2 | KTI12 | KTN1 | KTN1-AS1 | KXD1 | KY | KYAT1 | KYAT3 | KYNU | L-Type calcium channel | L-type voltage-dependent calcium channel complex | L1CAM | L1CAM-AS1 | L1TD1 | L2HGDH | L3HYPDH | L3MBTL1 | L3MBTL2 | L3MBTL3 | L3MBTL4 | L3MBTL4-AS1 | LACAT1 | LACC1 | LACRT | Lactate Dehydrogenase (LDH) | LACTB | LACTB2 | LACTB2-AS1 | LACTBL1 | LAD1 | LAG3 | LAGE3 | LAIR1